Research Publications

Our research group seeks to be productive, publishing the highest quality work possible.  We strive to ensure reproducibility of our results and rapid disclosure of our findings.  Find our publications from the last several years listed below and a complete list on Google Scholar via the button below.

All Publications

2025

284. Conor B. O'Herin and Seth M. Cohen*, "Target-protein Degradation of Metalloenzymes" Burger's Med. Chem. Drug Dis. Develop. 2025, accepted for publication. DOI: ?????????????

283. Anthony U. Mu, Vibhu Vardhan Singh, Hyunyong Kim, Dong Ju Lee, Namseo Kim, Christian X. Ruff, Aaron Levy, Thomas A. Young, Francesco Paesani, Seth M. Cohen*, Tod A. Pascal*, and Zheng Chen*, "Structure-Activity Relationships in Ether-Functionalized Solid-State Metal-Organic Framework Electrolytes" Chem. Mater. 2025, accepted for publication. DOI: 10.1021/ACS.CHEMMATER.4C03384

282. Minjung Kang, Po-An Lin, Jordan Bunch, Darren Lipomi, Arya Gaurav, and Seth M. Cohen*, "Impact of Grafting Density on the Assembly and Mechanical Properties of Self-Assembled Metal-Organic Framework Monolayers" J. Am. Chem. Soc. 2025, 147, 6966-6973. DOI: 10.1021/JACS.4C17748

281. Madison R. Esposito, Rajashree Newar, Min Kim*, and Seth M. Cohen*, "Incorporation of Low-Valent Metal Ions in Metal-Organic Frameworks and Coordination Polymers" Coord. Chem. Rev. 2025, 531, 216491. DOI: 10.1016/J.CCR.2025.216491

280. Hyunyong Kim and Seth M. Cohen*, "Metal-organic frameworks Generated from Oligomeric Ligands with Functionalized Tethers" Chem. Sci. 2025, 16, 2344-2350. DOI: 10.1039/D4SC06666A

2024

279. Debobroto Sensharma and Seth M. Cohen*, "Ligand Cross-Links as a Design Element in Oligo- and PolyMOFs" Chem. Sci. 2024, 15, 20448-20456. DOI: 10.1039/D4SC06109H

278. Prantik Mondal, Debobroto Sensharma, and Seth M. Cohen*, "Polymer-Metal-Organic Frameworks (polyMOFs) based on Tailor-made Poly(alkenamer)s" Chem. Mater. 2024, 36, 9696-9703. DOI: 10.1021/ACS.CHEMMATER.4C01794

277. Minjung Kang and Seth M. Cohen*, "Synthesis and Characterization of Self-Assembled Metal-Organic Framework Monolayers Using Polymer-Coated Particles" J. Vis. Exp. 2024, 208, e66497. DOI: 10.3791/66497

276. Prantik Mondal, Zachary Neuschuler, Dipendu Mandal, Ritchie E. Hernandez, and Seth M. Cohen*, "Reversible Postsynthetic Modification in a Metal-Organic Framework" Angew. Chem. Intl. Ed. 2024, e202317062.  DOI: 10.1002/ANIE.202317062

275. Hyunyong Kim and Seth M. Cohen*, "Metal-Organic Frameworks Constructed from Branched Oligomers" Inorg. Chem. 2024, 63, 1853-1857. DOI: 10.1021/ACS.INORGCHEM.3C03452

274. Alysia Kohlbrand, Ryjul Stokes, Banumathi Sankaran, and Seth M. Cohen*, "Structural Studies of Inhibitors with Clinically-relevant Influenza Endonuclease Variants" Biochemistry 2024, 63, 264-272. DOI: 10.1021/ACS.BIOCHEM.3C00536

2023

273. Prantik Mondal, Zhaoxi Zheng, Klaus Schmidt-Rohr, and Seth M. Cohen*, "Accessing Benzylic Amine and Azide Chemical Handles in Canonical Metal-Organic Frameworks" Chem. Mater. 2023, 35, 9702-9712. DOI: 10.1021/ACS.CHEMMATER.3C02143

272. Michelle R. Doyle, Selen Dirik, Angelica R. Martinez, Elizabeth A. Sneddon, Hyeonglim Seo, Seth M. Cohen, and Giordano de Guglielmo*, "Catechol-O-Methyltransferase Inhibition and Alcohol Use Disorder: Evaluating the Efficacy of Tolcapone in Ethanol-Dependent Rats" Neuropharm. 2023, 242, 109770. DOI: 10.1016/J.NEUROPHARM.2023.109770

271. Austin Wang, Kyle Barcus, and Seth M. Cohen*, "Quantifying Ligand Binding to the Surface of Metal-Organic Frameworks" J. Am Chem. Soc. 2023, 145, 16821-16827. DOI: 10.1021/JACS.3C04892

270. Guorui Cai, Amanda Chen, Sharon Lin, Dong Ju Lee, Kunpeng Yu, John Holoubek, Yijie Yin, Anthony Mu, Ying Meng, Ping Liu, Seth Cohen*, Tod Pascal*, and Zheng Chen*, "Unravelling Ultrafast Li-ion Transport in Functionalized Metal-organic Framework Based Battery Electrolytes" Nano Lett. 2023, 23, 7062-7069. DOI: 10.1021/ACS.NANOLETT.3C01825

269. Guorui Cai, Shatila Sarwar, Dong J. Lee, Seth Cohen, and Zheng Chen*, "Metal-organic Frameworks for Advanced Battery Chemistries" Encyclopedia of Materials: Electronics 2023, 3, 226-236. DOI: 10.1016/B978-0-12-819728-8.00033-4

268. Samuel E. Griffin, Grant P. Domecus, and Seth M. Cohen*, "Experimental Approaches for the Synthesis of Low-Valent Metal-Organic Frameworks from Multitopic Phosphine Linkers" J. Vis. Exp. 2023, e65317. DOI: 10.3791/65317

267.  Samuel E. Griffin, Grant P. Domecus, Clarissa E. Flores, R. Eric Sikma, Lauren Benz, and Seth M. Cohen*, "A Coordination Polymer of Vaska’s Complex as a Heterogeneous Catalyst for the Reductive Formation of Enamines from Amides" Angew. Chem. Intl. Ed. 2023, 62, e202301611. DOI: 10.1002/ANIE.202301611

266. Hyeonglim Seo, Alysia J. Kohlbrand, Ryjul W. Stokes, Jeewon Chung, and Seth M. Cohen*, "Masking thiol reactivity with thioamide, thiourea, and thiocarbamate-based MBPs" Chem. Commun. 2023, 59, 2283-2286. DOI: 10.1039/D2CC06596G

265. Johannes Karges and Seth M. Cohen*, "Rhenium(V) Complexes as Cysteine-Targeting Coordinate Covalent Warheads" J. Med. Chem. 2023, 66, 3088-3105. DOI: 10.1021/ACS.JMEDCHEM.2C02074

264. Conor B. O’Herin, Yuta W. Moriuchi, Troy A. Bemis, Alysia J. Kohlbrand, Michael D. Burkart,* and Seth M. Cohen*, "Development of Human Carbonic Anhydrase II Heterobifunctional Degraders" J. Med. Chem. 2023, 66, 2789-2803. DOI: 10.1021/ACS.JMEDCHEM.2C01843

263. Johannes Karges and Seth M. Cohen*, "Enantioselective Inhibition of the SARS-CoV-2 Main Protease with Rhenium(I) Picolinic Acid Complexes" Chem. Sci. 2023, 14, 711-720. DOI: 10.1039/D2SC05473F

262. Ryjul Stokes, Alysia Kohlbrand, Hyeonglim Seo, Banumathi Sankaran, Johannes Karges, and Seth M. Cohen*, "Carboxylic Acid Isostere Derivatives of Hydroxypyridinones as Core Scaffolds for Influenza Endonuclease Inhibitors" ACS Med. Chem. Lett. 2023, 14, 75-82. DOI: 10.1021/ACSMEDCHEMLETT.2C00434.

2022

261. Kyle Barcus, Po-An Lin, Yilong Zhou, Gaurav Arya, and Seth M. Cohen*, "The Influence of Polymer Characteristics on the Self-Assembly of Polymer-Grafted MOF Particles" ACS Nano 2022, 16, 18168-18177.  DOI: 10.1021/ACSNANO.2C05175

260. Prantik Mondal and Seth M. Cohen*, "Self-healing Mixed Matrix Membranes Containing Metal-Organic Frameworks" Chem. Sci. 2022, 13, 12127-12135.  DOI: 10.1039/D2SC04345A

259. Dong Ju Lee, Xiaolu Yu, Ronald E. Sikma, Mingqian Li, Seth M. Cohen, Guorui Cai, and Zheng Chen*, "Holistic Design Consideration of Metal-Organic Framework-Based Composite Membranes for Lithium-Sulfur Batteries" ACS App. Mater. Inter. 2022, 14, 34742-34749.  DOI: 10.1021/ACSAMI.2C08404

258. Ryan A. Dodson, Junkil Park, Jihan Kim, Matthew J. Cliffe, and Seth M. Cohen*, "Tethering Effects in Oligomer-Based Metal–Organic Frameworks" Inorg. Chem. 2022, 61, 12284-12292.  DOI: 10.1021/ACS.INORGCHEM.2C01567

257. Ronald E. Sikma, Krista P. Balto, Joshua S. Figueroa*, and Seth M. Cohen*, "Metal-Organic Frameworks with Low-Valent Metal Nodes" Angew. Chem. Int. Ed. 2022, 61, e202206353.  DOI: 10.1002/ANIE.202206353

256. Hyeonglim Seo, Moritz K. Jackl, Mark Kalaj, and Seth M. Cohen*, "Developing Metal-binding Isosteres of 8-Hydroxyquinoline as Metalloenzyme Inhibitor Scaffolds" Inorg. Chem. 2022, 61, 7631-7641.  DOI: 10.1021/ACS.INORGCHEM.2C00891

255. Johannes W. M. Osterrieth, et al., Seth M. Cohen, and David Fairen-Jimenez*, "How Reproducible are Surface Areas Calculated from the BET Equation?" Adv. Mater. 2022, 2201502.  DOI: 10.1002/ADMA.202201502

254. Johannes Karges, Ryjul W. Stokes, and Seth M. Cohen*, "Computational Prediction of the Binding Pose of Metal-Binding Pharmacophores" ACS Med. Chem. Lett. 2022, 13, 428-435.  DOI: 10.1021/ACSMEDCHEMLETT.1C00584

253. Johannes Karges and Seth M. Cohen*, "Preorganized Homochiral Pyrrole-Based Receptors That Display Enantioselective Anion Binding" Eur. J. Org. Chem. 2022, e202101346.  DOI: 10.1002/EJOC.202101346

252. Moritz K. Jackl, Hyeonglim Seo, Johannes Karges, Mark Kalaj, and Seth M. Cohen*, "Salicylate Metal-Binding Isosteres as Fragments for Metalloenzyme Inhibition" Chem. Sci. 2022, 13, 2128-2136.  DOI: 10.1039/D1SC06011B

251. Ronald E. Sikma and Seth M. Cohen*, "Metal-Organic Frameworks with Zero and Low Valent Metal Nodes Connected by Tetratopic Phosphine Ligands" Angew. Chem. Int. Ed. 2022, 61, e2021154 (highlighted as a 'Science Concentrate' on Jan. 17, 2022 by C&E News).  DOI: 10.1002/ANIE.202115454

250. Jie Zhu, Laura Samperisi, Mark Kalaj, Jerika A. Chiong, Jake B. Bailey, Zhiyin Zhang, Chung-Jui Yu, R. Eric Sikma, Xiaodong Zou, Seth M. Cohen, Zhehao Huang*, and F. Akif Tezcan*, "Metal-Hydrogen-Pi-Bonded Organic Frameworks" Dalton Trans. 2022, 51, 1927-1935.  DOI: 10.1039/D1DT04278E

249. Jessica C. Moreton, Jin Xiang Low, Katrina C. Penticoff, Seth M. Cohen, and Lauren Benz*, "An X-ray Photoelectron Spectroscopy Study of Postsynthetic Exchange in UiO-66" Langmuir 2022, 38, 1589-1599.  DOI: 10.1021/ACS.LANGMUIR1C03015

248. Sergio Ayala Jr. and Seth M. Cohen*, "PolyMOFs: Molecular Level Integration of MOFs and Polymers" Chapter 2 in Hybrid Metal-Organic Framework and Covalent Organic Framework Polymers, Smart Materials No. 39, published by the Royal Society of Chemistry, Ed. Bo Wang, 2022, 6-28.  DOI: 10.1039/9781839163456

2021

247. Samar S. Sandhu, Yugender Goud Kotagiri, P. U. Ashvin Iresh Fernando, Mark Kalaj, Nicholas Tostado, Hazhir Teymourian, Erik M. Alberts, Travis Thornell, Glen Jenness, Steven P. Harvey, Seth M. Cohen*, Lee C. Moores*, and Joseph Wang*, "Green MIP-202(Zr) Catalyst: Degradation and Thermally Robust Biomimetic Sensing of Nerve Agents" J. Am. Chem. Soc. 2021, 143, 18261-18271. DOI: 10.1021/JACS.1C08356

246. Johannes Karges*, Hyeonglim Seo, and Seth M. Cohen, "Synthesis of Tetranuclear Rhenium(I) Tricarbonyl Metallacycles" Dalton Trans. 2021, 50, 16147-16155.  DOI: 10.1039/D1DT02435C

245. Hyeonglim Seo, Kathleen Prosser, Mark Kalaj, Johannes Karges, Benjamin L. Dick, and Seth M. Cohen*, "Evaluating Metal-ligand Interactions of Metal-binding Isosteres Using Model Complexes" Inorg. Chem. 2021, 60, 17161-17172.  DOI:  10.1021/ACD.INORGCHEM.1C02433

244. Dominga Rogolino*, Lieve Naesens*, Jennifer Bartoli, Mauro Carcelli, Laura De Luca, Giorgio Pelosi, Ryjul W. Stokes, Ria Van Berwaer, Serena Vittorio, Annelies Stevaert, and Seth M. Cohen, "Exploration of the 2,3-Dihydroisoindole Pharmacophore for Inhibition of the Influenza Virus PA Endonuclease" Bioorg. Chem. 2021, 116, 105388.  DOI: 10.1016/J.BIOORG.2021.105388

243. Marcello B. Solomon, Carol Hua, Bun Chan, Tamara L. Church, Seth M. Cohen, Clifford P. Kubiak, Katrina A. Jolliffe, and Deanna M. D’Alessandro*, "The Electrochemical Reduction of a Flexible Mn(II) Salen-Based Metal-Organic Framework" Dalton Trans. 2021, 50, 12821-12825.  DOI: 10.1039/D1DT02589A

242. Seth M. Cohen* and Nathaniel L. Rosi*, "Postsynthetic Modification of Metal−Organic Frameworks" Inorg. Chem. 2021, 60, 11703-11705. (Guest Editor Introduction to Themed Issue). DOI: 10.1021/ACS.INORGCHEM.1C02159958

241. Kelly Hunter, Jackson Wagner, Mark Kalaj, Seth M. Cohen, Wei Xiong*, and Francesco Paesani*, "Simulation Meets Experiment: Unraveling the Properties of Water in Metal-Organic Frameworks Through Vibrational Spectroscopy" J. Phys. Chem. C 2021, 125, 12451-12460.  DOI: 10.1021/ACS.JPCC.1C03145

240. Johannes Karges* and Seth M. Cohen*, "Metal Complexes as Antiviral Agents for SARS-CoV-2" ChemBioChem 2021, 22, 2600-2607.  DOI: 10.1002/cbic.202100186

239. Ashleigh Castner, Ben A. Johnson, Seth M. Cohen, Sascha Ott*, "Mimicking the Electron Transport Chain and Active Site of [FeFe] Hydrogenases in one Metal-Organic Framework: Factors that Influence Charge Transport" J. Am. Chem. Soc. 2021, 21, 7991-7999.  DOI: 10.1021/JACS.1C01361

238. Huan Zhang, Kundi Yang, Abbie Steinbrunner, Cecily Pryor, Maya Vulcan, Claire Kemp, Diego Orea, Chathura Paththamperuma, Zishuo Cheng, Allie Y. Chen, Seth M. Cohen, Richard C. Page, David L. Tierney, Michael W. Crowder*, "Spectroscopic and Biochemical Characterization of Metallo-b-lactamase IMP-1 with Dicarboxylic, Sulfonyl, and Thiol Inhibitors" Bioorg. Med. Chem. 2021, 40, 116183.  DOI: 10.1016/J.BMC.2021.116183

237. Kathleen E. Prosser, Alysia J. Kolhbrand, Heonglim Seo, Mark Kalaj, and Seth M. Cohen*, "19F-Tagged Metal Binding Pharmacophores for NMR Screening of Metalloenzymes" Chem. Commun. 2021, 57, 4934-4937.  DOI: 10.1039/D1CC01231B

236. Joseph M. Palomba, David M. Wirth, Jin Yeong Kim, Mark Kalaj, Evan M. Clarke, Gregory W. Peterson, Jonathan K. Pokorski, and Seth M. Cohen*, "Strong, Ductile MOF-Polyurethane Urea Composites" Chem. Mater. 2021, 33, 3164-3171.  DOI: 10.1021/ACS.CHEMMATER.0C04874

235. Ralph Freund, Stefano Canossa, Seth M. Cohen, Wei Yan, Hexiang Deng, Vincent Guillerm, Mohamed Eddaoudi, David G. Madden, David Fairen-Jimenez, Hao Lyu, Lauren K. Macreadie, Zhe Ji, Yuanyuan Zhang, Bo Wang, Frederik Haase, Christof Wöll, Orysia Zaremba, Jacopo Andreo, Stefan Wuttke, and Christian S. Diercks*, "25 years of Reticular Chemistry" Angew. Chem. Intl. Ed. 2021, 60, 23946-23974.  DOI: 10.1002/ANIE.202101644

234. Johannes Karges, Ryjul W. Stokes, and Seth M. Cohen*, "Metal Complexes for Therapeutic Applications" Trends Chem. 2021, 3, 523-534.  DOI: 10.1016/J.TRECHM.2021.03.006

233. Jin Yeong Kim, Kyle Barcus, and Seth M. Cohen*, "Controlled Two-Dimensional Alignment of Metal-organic Frameworks in Polymer Films" J. Am. Chem. Soc. 2021, 143, 3703-3706.  DOI: 10.1021/JACS.0C13459

232. Rebecca N. Adamek, Caitlin N. Suire, Ryjul W. Stokes, Monica K. Brizuela, Seth M. Cohen*, and Malcolm A. Leissring*, "Hydroxypyridinethione Inhibitors of Human Insulin-Degrading Enzyme" ChemMedChem 2021, 16, 1775-1787.  DOI: 10.1002/CMDC.202100111

231. Johannes Karges, Mark Kalaj, Milan Gembicky, and Seth M. Cohen*, "Re(I) Tricarbonyl Complexes as Coordinate Covalent Inhibitors for the SARS-CoV-2 Main Cysteine Protease" Angew. Chem. Intl. Ed. 2021, 60, 10716-10723.  DOI: 10.1002/ANIE.202016768

230. Jin Yeong Kim, Evan M. Clarke, and Seth M. Cohen*, "Current Trends in the Postsynthetic Modification of Framework Materials" Comprehensive Coordination Chemistry III 2021, 1, 1055-1073.  DOI: 10.1016/B978-0-08-102688-5.00087-8

229. Johannes Karges, Ryjul W. Stokes, and Seth M. Cohen*, "Photorelease of a Metal-Binding Pharmacophore from a Ru(II) Polypyridine Complex" Dalton Trans. 2021, 50, 2757-2765.  DOI: 10.1039/D0DT04290K

228. Yi-Sheng Lu, Sanahan Vijayakumar, Arnaud Chaix, Brian Pimentel, Kyle C. Bentz, Sheng Li, Adriano Chan, Charlotte Wahl, James Ha, Deborah Hunka, Gerry Boss, Seth M. Cohen, and Michael Sailor*, "Remote Detection of HCN, HF, and Nerve Agent Vapors Based on Self-Referencing, Dye-Impregnated Porous Silicon Photonic Crystals" ACS Sensors 2021, 6, 418-428.  DOI: 10.1021/ACSSENSORS.0C01931

2020

227. Xinyi Gong, Karthikeyan Gnanasekaran, Zhijie Chen, Lee Robison, Megan C. Wasson, Kyle C. Bentz, Seth M. Cohen*, Omar K. Farha*, and Nathan C. Gianneschi*, "Insights into the Structure and Dynamics of Metal–Organic Frameworks via Transmission Electron Microscopy" J. Am. Chem. Soc. 2020, 142, 17224-17235.  DOI: 10.1021/JACS.0C08773

226. Kyle C. Bentz, Karthikeyan Gnanasekaran, Jake B. Bailey, Sergio Ayala Jr., F. Akif Tezcan, Nathan C. Gianneschi*, and Seth M. Cohen*, "Inside polyMOFs: Layered Structures in Polymer-Based Metal-Organic Frameworks" Chem. Sci. 2020, 11, 10523-10528.  DOI: 10.1039/D0SC03651J

225. Lucy Lin, Margaret Olson, Takashi Sugane, Lewis Turner, Margarita Tararina, Alexander L. Nielsen, Elbek Kurbanov, Sabine Pellett, Eric Johnson, Seth M. Cohen, Karen Allen, and Kim Janda*, "A Catch and Anchor Approach to Combat both Toxicity and Longevity of Botulinum Toxin A" J. Med. Chem. 2020, 63, 11100-11120.  DOI: 10.1021/ACS.JMEDCHEM.0C01006

224. Kyle S. Barcus and Seth M. Cohen*, "Free-Standing Metal-Organic Framework (MOF) Monolayers by Self-Assembly of Polymer-Grafted Nanoparticles" Chem. Sci. 2020, 11, 8433-8437.  DOI: 10.1039/D0SC03318A

223. Rebecca N. Adamek, Paul Ludford, Stephanie M Duggan, Yitzhak Tor*, and Seth M. Cohen*, "Identification of Adenosine Deaminase Inhibitors by Metal-binding Pharmacophore Screening" ChemMedChem 2020, 15, 2151-2156.  DOI: 10.1002/CMDC.202000271

222. Caitlyn A. Thomas, Zishuo Cheng, Kundi Yang, Elle Hellwarth, Cole J. Yurkiewicz, Faith M. Baxter, Sarah A. Fullington, Spencer A. Klinsky, Jen L. Otto, Allie Y. Chen, Seth M. Cohen, and Michael W. Crowder*, "Probing the mechanisms of inhibition for various inhibitors of metallo-β- lactamases VIM-2 and NDM-1" J. Inorg. Biochem. 2020, 210, 111123.  DOI: 10.1016/J.JINORGBIO.2020.111123

221. Mark Kalaj and Seth M. Cohen*, "Postsynthetic Modification: An Enabling Technology for the Advancement of Metal-Organic Frameworks" ACS Cent. Sci. 2020, 6, 1046-1057.  DOI: 10.1021/ACSCENTSCI.0C00690

220. Mark Kalaj, Kathleen E. Prosser, and Seth M. Cohen*, "Room Temperature Aqueous Synthesis of UiO-66 Derivatives via Postsynthetic Exchange" Dalton Trans. 2020, 49, 8841-8845.  DOI: 10.1039/D0DT01939A

219. Benjamin L. Dick, Ashay Patel, and Seth M. Cohen*, "Effect of Heterocycle Content on Metal Binding Isostere Coordination" Chem. Sci. 2020, 11, 6907-6914.  DOI: 10.1039/d0SC02717K

218. Paulo G. M. Mileo, Shichen Yuan, Sergio Ayala, Pu Duan, Rocio Semino, Seth M. Cohen*, Klaus Schmidt-Rohr*, and Guillaume Maurin*, " Structure of the Polymer Backbones in polyMOF Materials" J. Am. Chem. Soc. 2020, 142, 10863-10868.  DOI: 10.1021/JACS.0C04546

217. Kathleen E. Prosser, Ryjul W. Stokes, and Seth M. Cohen*, "Evaluation of 3-Dimensionality in Existing Approved and Experimental Drug Space" ACS Med. Chem. Lett. 2020, 11, 1292-1298.  DOI: 10.1021/ACSMEDCHEMLETT.0C00121

216. Mark Kalaj and Seth M. Cohen*, "Spray Coating of Catalytically Active MOF-Polythiourea through Postsynthetic Polymerization" Angew. Chem. Intl. Ed. 2020, 59, 13984-13989.  DOI: 10.1002/ANIE.202004205

215. Allie Y. Chen, Caitlyn Thomas, Pei W. Thomas, Kundi Yang, Zishou Cheng, Walter Fast*, Michael Crowder*, and Seth M. Cohen*, "Iminodiacetic Acid as a Novel Metal-Binding Pharmacophore for New Delhi Metallo-β-lactamase Inhibitor Development" ChemMedChem 2020, 15, 1272-1282.  DOI: 10.1002/CMDC.202000123

214. Jerika Chiong, Jie Zhu, Jake Bailey, Mark Kalaj, Rohit Subramanian, Wenqian Xu, Seth M. Cohen, F. Akif Tezcan*, "An Exceptionally Stable Metal-Organic Framework Constructed from Chelate-based Metal-Organic Polyhedra" J. Am. Chem. Soc. 2020, 142, 6907-6912.  DOI: 10.1021/JACS.0C01626

213. Jessica C. Moreton, Joseph M. Palomba, and Seth M. Cohen*, "Liquid-Phase Applications of Metal-Organic Framework Mixed-Matrix Membranes Prepared from Poly(ethylene-co-vinyl acetate)" ACS App. Poly. Mater. 2020, 2, 2063-2069.  DOI: 10.1021/ACSAPM.0C00230

212. Joseph M. Palomba, Mark Kalaj, and Seth M. Cohen*, "High-throughput Screening of MOFs for Breakdown of V-series Nerve Agents" ACS App. Mater. Inter. 2020, 12, 14672-14677.  DOI: 10.1021/ACSAMI.9B21693

211. Christine N. Morrison, Kathleen E. Prosser, Ryjul W. Stokes, Anna Cordes, Nils Metzler-Nolte, and Seth M. Cohen*, "Expanding Medicinal Chemistry into 3D Space: Metallofragments as 3D Scaffolds for Fragment-Based Drug Discovery" Chem. Sci. 2020, 11, 1216-1225 (selected as 'Pick of the Week' Jan. 15, 2020 by Chem. Sci.).  DOI: 10.1039/C9SC05586J 

210. Mark Kalaj, Kyle C. Bentz, Sergio Ayala Jr., Joseph M. Palomba, Kyle S. Barcus, Yuji Katayama, and Seth M. Cohen*, "MOF-Polymer Hybrid Materials: From Simple Composites to Tailored Architectures" Chem. Rev. 2020, 120, 8267-8302.  DOI: 10.1021/ACS.CHEMREV.9B00575

2015-2019

209. Yuji Katayama, Mark Kalaj, Kyle S. Barcus, and Seth M. Cohen*, "Self-Assembly of Metal-Organic Framework (MOF) Nanoparticle Monolayers and Free-Standing Multilayers" J. Am. Chem. Soc. 2019, 141, 20000-20003.  DOI: 10.1021/JACS.9B10966

208. Cy V. Credille, Christine N. Morrison, Ryjul W Stokes, Benjamin L. Dick, Yifan Feng, Jiaxing Sun, Yao Chen*, and. Seth M. Cohen*, "SAR Exploration of Tight-Binding Inhibitors of Influenza Virus PA Endonuclease" J. Med. Chem. 2019, 62, 9438-9449. DOI: 10.1021/ACS.JMEDCHEM.9b00747

207. Allie Y. Chen, Pei W. Thomas, Zishuo Cheng, Nasa Y. Xu, David L. Tierney, William M. Crowder*, Walter Fast*, and Seth M. Cohen*, "Investigation of Dipicolinic Acid Isosteres for the Inhibition of Metallo‐β‐Lactamases. ChemMedChem 2019, 14, 1271-1282.  DOI:  10.1002/CMDC.201900172

206. Kyle C. Bentz, Sergio Ayala, Mark Kalaj, and Seth M. Cohen*, "Polyacids as Modulators for the Synthesis of UiO-66" Aust. J. Chem. 2019, 72, 848-851.  DOI:  10.1071/CH19271

205. Mark Kalaj, Joseph M. Palomba, Kyle C, Bentz, and Seth M. Cohen*, "Multiple Functional Groups in UiO-66 Improve Chemical Warfare Agent Simulant Degradation" Chem. Commun. 2019, 55, 5367-5370.  DOI: 10.1039/C9CC02252J

204. Remo N. Widmer, Giulio I. Lampronti, Simone Anzellini, Romain Gaillac, Stefan Farsang, Chao Zhou, Ana M. Belenguer, Craig Wilson, Hannah Palmer, Annette K. Kleppe, Michael T. Wharmby, Xiao Yu, Seth M. Cohen, Shane G. Telfer, Simon A. T. Redfern, François-Xavier Coudert, Simon G. MacLeod, and Thomas D. Bennett*, “Pressure Promoted Low-Temperature Melting of Metal-Organic Frameworks” Nat. Mater. 2019, 18, 370-376. DOI: 10.1038/S41563-019-0317-4

203. Yuji Katayama, Kyle C. Bentz, and Seth M. Cohen*, “Defect-Free MOF-Based Mixed Matrix Membranes Obtained by Corona Crosslinking” ACS App. Mater. Inter. 2019, 11, 13029-13037.  DOI: 10.1021/ACSAMI.9b02539

202. Mark Kalaj, Mohammad R. Momeni, Kyle C. Bentz, Kyle S. Barcus, Joseph M. Palomba, Francesco Paesani, and Seth M. Cohen*, “Halogen bonding in UiO-66 Frameworks Promotes Superior Chemical Warfare Agent Simulant Degradation” Chem. Commun. 2019, 55, 3481-3484.  DOI: 10.1002/cbic.202100186

201. Allie Y. Chen, Rebecca N. Adamek, Benjamin L. Dick, Cy V. Credille, Christine N. Morrison, and Seth M. Cohen*, “Targeting Metalloenzymes for Therapeutic Intervention” Chem. Rev. 2019, 119, 1323-1455. DOI: 10.1021/ACS.CHEMREV.8B00201

200. Louis Longley, Sean M. Collins, Shichun Li, Glen J. Smales, Ilknur Erucar, Ang Qiao, Jingwei Hou, Cara M. Doherty, Aaron W. Thornton, Anita J. Hill, Xiao Yu, Nicholas J. Terrill, Andrew J. Smith, Seth M. Cohen, Paul A. Midgley, David A. Keen, Shane G. Telfer, and Thomas D. Bennett*, “Flux Melting of Metal-Organic Frameworks” Chem. Sci. 2019, 10, 3592-3601.

199. Christian L. Perez, Amanda M. Barkley-Levenson, Benjamin L. Dick, Peter F. Glatt, Yadira Martinez, Dionicio Siegel, Jeremiah D. Momper, Abraham A. Palmer*, and Seth M. Cohen*, “A Metal-Binding Pharmacophore Library Yields the Discovery of a Glyoxalase 1 Inhibitor” J. Med. Chem. 2019, 62, 1609- 1625.

198. Mark Kalaj, Michael S. Denny, Jr., Kyle C. Bentz, Joseph M. Palomba, and Seth M. Cohen*, "Nylon-MOF Composites via Postsynthetic Polymerization" Angew. Chem. Intl. Ed. 2019, 58, 2336-2340.

197. Sergio Ayala Jr., Kyle C. Bentz, and Seth M. Cohen*, "Block co-polyMOFs: Morphology Control of Polymer- MOF Hybrid Materials" Chem. Sci. 2019, 10, 1746-1753.

196. Cy V. Credille, Benjamin L. Dick, Ryjul W. Stokes, Rebecca N. Adamek, Nicholas Wu, Ian Wilson, and Seth M. Cohen*, "Structure-Activity Relationships in Metal-Binding Pharmacophores for Influenza Endonuclease" J. Med. Chem. 2018, 61, 10206-10217.

195. Michael S. Denny, Jr., Mark Kalaj, Kyle C. Bentz, and S. M. Cohen*, “Multicomponent Metal–organic Framework Membranes for Advanced Functional Composites” Chem. Sci. 2018, 9, 8842-8849.

194. Joseph M. Palomba, Sergio Ayala Jr., and Seth M. Cohen*, “polyMOF Formation from Kinked Polymer Ligands via ortho-Substitution” Israel J. Chem. 2018, 58, 1123-1126.

193. Jing Li,* Yaru Zhang, Bruno Da Silva Sil Dos Santos, Feng Wang, Yuyong Ma, Christian Perez, Yanling Yang, Junmin Peng, Seth M. Cohen, Tsui-Fen Chou, Stephen T. Hilton, and Raymond J. Deshaies, “Epidithiodiketopiperazines Inhibit Protein Degradation by Targeting Proteasome Deubiquitinase Rpn11” Cell Chem. Biol. 2018, 25, 1350-1358.

192. Marcello B. Solomon, Aditya Rawal, James M. Hook, Seth M. Cohen, Clifford P. Kubiak, Katrina A. Jolliffe,* and Deanna M. D'Alessandro*, “Electroactive Co(III) Salen Metal Complexes and the Electrophoretic Deposition of their Porous Organic Polymers onto Glassy Carbon” RSC Adv. 2018, 8, 24128-24142.

191. Benjamin L. Dick and Seth M. Cohen*, "Metal-Binding Isosteres as New Scaffolds for Metalloenzyme Inhibitors" Inorg. Chem. 2018, 57, 9538-9543.

190. Rebecca N. Adamek, Cy V. Credille, Benjamin L. Dick, and Seth M. Cohen*, "Isosteres of Hydroxypyridinethione as Druglike Pharmacophores for Metalloenzyme Inhibition" J. Biol. Inorg. Chem. 2018, 23, 1129-1138.

189. Joseph M. Palomba, Cy V. Credille, Mark Kalaj, Jared B. DeCoste, Gregory W. Peterson, Trenton M. Tovar, and Seth M. Cohen*, "High-Throughput Screening of Solid-State Catalysts for Nerve Agent Degradation" Chem. Commun. 2018, 54, 5768-5771.

188. Ben A. Johnson, Asamanjoy Bhunia, Honghan Fei, Seth M. Cohen, and Sascha Ott*, "Development of a UiO-type Thin Film Electrocatalysis Platform with Redox Active Linkers" J. Am. Chem. Soc. 2018, 140, 2985-2994.

187. Michael S. Denny, Jr., Lucas R. Parent, Joseph P. Patterson, Santosh Kumar Meena, Huy Pham, Patricia Abellan, Quentin M. Ramasse, Francesco Paesani, Nathan C. Gianneschi,* and Seth M. Cohen*, "Transmission Electron Microscopy Reveals Deposition of Metal Oxide Coatings onto Metal−Organic Frameworks" J. Am. Chem. Soc. 2018, 140, 1348-1357.

186. [RETRACTED] Le Wang, Douglas W. Agnew, Xiao Yu, Josh S. Figueroa*, and Seth M. Cohen*, “A Metal-Organic Framework with Exceptional Activity for C–H Bond Amination” Angew. Chem. Int. Ed. 2018, 57, 511-515.

185. Rocio Semino, Jessica C. Moreton, N. A. Ramsahye, Seth M. Cohen*, and Guillaume Maurin*, “Understanding the Origins of Metal-Organic Framework/Polymer Compatibility” Chem. Sci. 2018, 9, 315- 324.

184. Le Wang, Curtis E. Moore, and Seth M. Cohen*, “Coordinative Alignment to Achieve Ordered Guest Molecules in a Versatile Molecular Crystalline Sponge” Cryst. Growth Des. 2017, 17, 6174-6177.

183. Lucas R. Parent, Huy Pham, Joseph P. Patterson, Michael S. Denny, Jr., Seth M. Cohen, Nathan C. Gianneschi*, and Francesco Paesani*, “Pore Breathing of Metal-Organic Frameworks by Environmental Transmission Electron Microscopy” J. Am. Chem. Soc. 2017, 139, 13973-13976.

182. Giulia E. M. Schukraft, Sergio Ayala, Jr., Benjamin L. Dick, and Seth M. Cohen*, “Isoreticular Expansion of polyMOFs Achieves High Surface Area Materials” Chem. Commun. 2017, 53, 10684-10687.

181. Whitney R. Craig, Amy R. Marts, Tessa W. Baker, David P. Martin, Garrett C. Reed, Daniel T. DeGenova, Robert M. McCarrick, Michael W. Crowder*, Seth M. Cohen*, and David L. Tierney*, “Substituent Effects on the Coordination Chemistry of Metal-Binding Pharmacophores” Inorg. Chem. 2017, 56, 11721-11728.

180. Allie Y. Chen, Pei W. Thomas, Alesha C. Stewart, Alexander Bergstrom, Zishuo Cheng, Callie Miller, Christopher R. Bethel, Steven H. Marshall, Cy V. Credille, Christopher L. Riley, Richard C. Page, Robert A. Bonomo*, Michael W. Crowder*, David L. Tierney*, Walter Fast*, and Seth M. Cohen*, “Dipicolinic Acid Derivatives as Inhibitors of New Delhi Metallo-β-lactamase-1” J. Med. Chem. 2017, 60, 7267-7283.

179. Benjamin L. Dick, Ashay Patel, J. Andrew McCammon, and Seth M. Cohen*, “Effect of Donor Atom Identity on Metal Binding Pharmacophore Coordination” J. Biol. Inorg. Chem. 2017, 22, 605-613.

178. Sergio Ayala, Jr., Zhenjie Zhang, and Seth M. Cohen*, “Hierarchical Structure and Porosity in UiO-66 polyMOFs” Chem. Commun. 2017, 53, 3058-3061.

177. Yao Chen*, Barry Lai, Zhenjie Zhang, and Seth M. Cohen*, “The Effect of Metalloprotein Inhibitors on Cellular Metal Ion Content and Distribution” Metallomics 2017, 9, 250-257.

176. Jing Li, Tanya Yakushi, Frank Parlati, Andrew L. Mackinnon, Christian Perez, Yuyong Ma, Kyle P. Carter, Sharon Colayco, Gavin Magnuson, Brock Brown, Kevin Nguyen, Stefan Vasile, Eigo Suyama, Layton H. Smith, Eduard Sergienko, Anthony B. Pinkerton, Thomas D.Y. Chung, Amy E. Palmer, Ian Pass, Sonja Hess, Seth M. Cohen, and Raymond J. Deshaies*, “Capzimin is a Potent and Specific Inhibitor of Proteasome Isopeptidase Rpn11” Nat. Chem. Biol. 2017, 13, 486-496.

175. Christian Perez, Jing Li, Frank Parlati, Matthieu Rouffet, Yuyong Ma, Andrew Mackinnon, Tsui-Fen Chou, Raymond Deshaies*, and Seth M. Cohen*, “Discovery of an Inhibitor of the Proteasome Subunit Rpn11” J. Med. Chem. 2017, 60, 1343-1361.

174. Jinxing Li, Xiao Yu, Mingli Xu, Wenjuan Liu, Elodie Sandraz, Hsin Lan, Joseph Wang*, and Seth M. Cohen*, “Metal−Organic Frameworks as Micromotors with Tunable Engines” J. Am. Chem. Soc. 2017, 139, 611-614.

173. Jessica C. Moreton, Mike S. Denny, Jr., and Seth M. Cohen*, “High MOF Loading in Mixed-matrix Membranes Utilizing Styrene/butadiene Copolymers” Chem. Commun. 2016, 52, 14376-14379.

172. Xiao Yu and Seth M. Cohen*, “Photocatalytic Metal−Organic Frameworks for Selective 2,2,2- Trifluoroethylation of Styrenes” J. Am. Chem. Soc. 2016, 138, 12320-12323.

171. Teng-Hao Chen, Le Wang, Jonathan Trueblood, Vicki Grassian, and Seth M. Cohen*, “Poly(isophthalic acid)(ethylene oxide) as a Macromolecular Modulator for Metal−Organic Polyhedra” J. Am. Chem. Soc. 2016, 138, 9646-9654.

170. Xiaoping Zhang, Zhenjie Zhang, Jake A. Boissonnault, and Seth M. Cohen*, “Design and Synthesis of Squaramide-Based MOFs as Efficient Hydrogen-Bonding Organocatalysts” Chem. Commun. 2016, 52, 8585-8588.

169. Cy V. Credille, Yao Chen, and Seth M. Cohen*, “Fragment-based Identification of Influenza Endonuclease Inhibitors” J. Med. Chem. 2016, 59, 6444-6454.

168. Jared B. DeCoste*, Michael. S. Denny, Jr., Gregory W. Peterson, John J. Mahle, and Seth M. Cohen*, “Enhanced Aging Properties of HKUST-1 in Hydrophobic Mixed-Matrix Membranes for Ammonia Adsorption” Chem. Sci. 2016, 7, 2711-2716.

167. Teng-Hao Chen, Andreas Schneemann, Roland A. Fischer, Seth M. Cohen*, “Metal−organic Frameworks Constructed from Crown Ether-based 1,4-Benzenedicarboxylic Acid Derivatives” Dalton Trans. 2016, 45, 3063-3069.

166. Zhenjie Zhang, Ha Thi Hoang Nguyen, Stephen A. Miller, Ann Ploskonka, Jared DeCoste, Seth M. Cohen*, “Polymer-Metal-Organic Frameworks (polyMOFs) as Water Tolerant Materials for Selective Carbon Dioxide Separations” J. Am. Chem. Soc. 2016, 138, 920-925.

165. Kevin B. Daniel, Cassandra E. Callmann, Nathan C. Gianneschi*, and Seth M. Cohen*, “Dual-Responsive Nanoparticles Release Cargo Upon Exposure to Matrix Metalloproteinase and Reactive Oxygen Species” Chem. Commun. 2016, 52, 2126-2128.

164. Yeob Lee, Sangjun Kim, Honghan Fei, Jeung Ku Kang*, and Seth M. Cohen*, “Photocatalytic CO2 Reduction Using Visible Light by Metal-monocatecholato Species in a Metal-organic Framework” Chem. Commun. 2015, 51, 16549-16552.

163. Yao Chen and Seth M. Cohen*, “Investigating the Selectivity of Metalloenzyme Inhibitors in the Presence of Competing Metalloproteins” ChemMedChem 2015, 10, 1733-1738.

162. Marco Taddei*, Phuong V. Dau, Seth M. Cohen, Marco Ranocchiari, Jeroen A. van Bokhoven, Ferdinando Costantino, Stefano Sabatini, and Riccardo Vivani, “Efficient Microwave Assisted Synthesis of Metal- organic Framework UiO-66: Optimization and Scale Up” Dalton Trans. 2015, 44, 14019-14026.

161. Honghan Fei, Matthew D. Sampson, Yeob Lee, Clifford P. Kubiak*, and Seth M. Cohen*, “Photocatalytic CO2 Reduction to Formate Using a Mn(I) Molecular Catalyst in a Robust Metal-Organic Framework” Inorg. Chem. 2015, 54, 6821-6828.

160. Mike S. Denny, Jr. and Seth M. Cohen*, "In Situ Modification of Metal-Organic Frameworks in Mixed- Matrix Membranes" Angew. Chem. Int. Ed. 2015, 54, 9029-9032.

159. Joseph P. Patterson, Patricia Abellan, Mike S. Denny, Jr., Chiwoo Park, Nigel D. Browning, Seth M. Cohen, James E. Evans, and Nathan C. Gianneschi*, "Observing the Growth of Metal-Organic Frameworks by In- Situ Liquid Cell TEM" J. Am. Chem. Soc. 2015, 137, 7322-7328.

158. Xiao Yu and Seth Cohen*, “Photocatalytic Metal-organic Frameworks for the Aerobic Oxidation of Arylboronic Acids” Chem. Commun. 2015, 51, 9880-9883.

157. Kevin Daniel, Eric Sullivan, Yao Chen, Joshua Chan, Patricia Jennings, Carol Fierke*, Seth Cohen*, "Dual- Mode HDAC Prodrug for Covalent Modification and Subsequent Inhibitor Release" J. Med. Chem. 2015, 58, 4812-4821.

156. Zhenjie Zhang, Ha Thi Hoang Nguyen, Stephen A. Miller, and Seth M. Cohen*, "polyMOFs: A Class of Interconvertible Polymer-MOF Hybrid Materials" Angew. Chem. Int. Ed. 2015, 54, 6152-6157.

155. Christian Perez, Jean-Philippe Monserrat, Yao Chen, and Seth M. Cohen*, "Exploring Hydrogen Peroxide Responsive Thiazolidinone-Based Prodrugs" Chem. Commun. 2015, 51, 7116-7119.

154. Yeob Lee, Sangjun Kim, Jeung Ku Kang*, and Seth M. Cohen*, “Photocatalytic CO2 reduction by a mixed metal (Zr/Ti), mixed ligand metal-organic framework under visible light irradiation” Chem. Commun. 2015, 51, 5735-5738.

153. Phuong V. Dau and Seth M. Cohen*, “A Bifunctional, Site-Isolated Metal-organic Framework-based Tandem Catalyst” Inorg. Chem. 2015, 54, 3134-3138.

152. Honghan Fei and Seth M. Cohen*, “Metalation of a Thiocatechol-Functionalized Zr(IV)-based Metal-Organic Framework for Selective C-H Functionalization” J. Am. Chem. Soc. 2015, 137, 2191-2194.

151. JaeWook Shin, Min Kim, Jordi Cirera, Shawn Chen, Gregory J. Halder, Thomas A. Yersak, Francesco Paesani, Seth M. Cohen, and Ying Shirley Meng*, “MIL-101(Fe) as a Lithium-ion Battery Electrode Material: Relaxation and Intercalation Mechanism During Lithium Insertion” J. Mater. Chem. A 2015, 3, 4738-4744.

150. John F. Cahill, Honghan Fei, Seth M. Cohen, and Kimberly A. Prather*, “Characterization of Core-shell MOF Particles by Depth Profiling Experiments Using on-line Single Particle Mass Spectrometry” Analyst 2015, 140, 1510-1515.

149. Honghan Fei, Sonja Pullen, Andreas Wagner, Sascha Ott*, and Seth M. Cohen*, “Functionalization of Robust Zr(IV)-based Metal-Organic Framework Films via a Postsynthetic Ligand Exchange” Chem. Commun. 2015, 51, 66-69.