COHEN RESEARCH GROUP

Publications

262. Johannes Karges and Seth M. Cohen*, "Enantioselective Inhibition of the SARS-CoV-2 Main Protease with Rhenium(I) Picolinic Acid Complexes" Chem. Sci. 2022, online contents.
DOI: 10.1039/D2SC05473F

261. Ryjul Stokes, Alysia Kohlbrand, Hyeonglim Seo, Banumathi Sankaran, Johannes Karges, and Seth M. Cohen*, "Carboxylic Acid Isostere Derivatives of Hydroxypyridinones as Core Scaffolds for Influenza Endonuclease Inhibitors" ACS Med. Chem. Lett. 2022, accepted for publication.
DOI: 10.1021/ACSMEDCHEMLETT.2C00434


260. Kyle Barcus, Po-An Lin, Yilong Zhou, Gaurav Arya, and Seth M. Cohen*, "The Influence of Polymer Characteristics on the Self-Assembly of Polymer-Grafted MOF Particles" ACS Nano 2022, 16, 18168−18177.
DOI: 10.1021/ACSNANO.2C05175

259. Prantik Mondal and Seth M. Cohen*, "Self-healing Mixed Matrix Membranes Containing Metal-Organic Frameworks" Chem. Sci. 2022, 13, 12127-12135.
DOI: 10.1039/D2SC04345A

258. Dong Ju Lee, Xiaolu Yu, Ronald E. Sikma, Mingqian Li, Seth M. Cohen, Guorui Cai, and Zheng Chen*, "Holistic Design Consideration of Metal-Organic Framework-Based Composite Membranes for Lithium-Sulfur Batteries" ACS App. Mater. Inter. 2022, 14, 34742-34749.
DOI: 10.1021/ACSAMI.2C08404

257. Ryan A. Dodson, Junkil Park, Jihan Kim, Matthew J. Cliffe, and Seth M. Cohen*, "Tethering Effects in Oligomer-Based Metal–Organic Frameworks" Inorg. Chem. 2022, 61, 12284-12292.
DOI: 10.1021/ACS.INORGCHEM.2C01567

256. Ronald E. Sikma, Krista P. Balto, Joshua S. Figueroa*, and Seth M. Cohen*, "Metal-Organic Frameworks with Low-Valent Metal Nodes" Angew. Chem. Int. Ed. 2022, 61, e202206353.
DOI: 10.1002/ANIE.202206353

255. Hyeonglim Seo, Moritz K. Jackl, Mark Kalaj, and Seth M. Cohen*, "Developing Metal-binding Isosteres of 8-Hydroxyquinoline as Metalloenzyme Inhibitor Scaffolds" Inorg. Chem. 2022, 61, 7631-7641.
DOI: 10.1021/ACS.INORGCHEM.2C00891

254. Johannes W. M. Osterrieth, et al., Seth M. Cohen, and David Fairen-Jimenez*, "How Reproducible are Surface Areas Calculated from the BET Equation?" Adv. Mater. 2022, 2201502.
DOI: 10.1002/ADMA.202201502

253. Johannes Karges, Ryjul W. Stokes, and Seth M. Cohen*, "Computational Prediction of the Binding Pose of Metal-Binding Pharmacophores" ACS Med. Chem. Lett. 2022, 13, 428-435.
DOI: 10.1021/ACSMEDCHEMLETT.1C00584

252. Johannes Karges and Seth M. Cohen*, "Preorganized Homochiral Pyrrole-Based Receptors That Display Enantioselective Anion Binding" Eur. J. Org. Chem. 2022, e202101346.
DOI: 10.1002/EJOC.202101346

251. Moritz K. Jackl, Hyeonglim Seo, Johannes Karges, Mark Kalaj, and Seth M. Cohen*, "Salicylate Metal-Binding Isosteres as Fragments for Metalloenzyme Inhibition" Chem. Sci. 2022, 13, 2128-2136.
DOI: 10.1039/D1SC06011B

250. Ronald E. Sikma and Seth M. Cohen*, "Metal-Organic Frameworks with Zero and Low Valent Metal Nodes Connected by Tetratopic Phosphine Ligands" Angew. Chem. Int. Ed. 2022, 61, e2021154 (highlighted as a 'Science Concentrate' on Jan. 17, 2022 by C&E News).
DOI: 10.1002/ANIE.202115454

249. Jie Zhu, Laura Samperisi, Mark Kalaj, Jerika A. Chiong, Jake B. Bailey, Zhiyin Zhang, Chung-Jui Yu, R. Eric Sikma, Xiaodong Zou, Seth M. Cohen, Zhehao Huang*, and F. Akif Tezcan*, "Metal-Hydrogen-Pi-Bonded Organic Frameworks" Dalton Trans. 2022, 51, 1927-1935.
DOI: 10.1039/D1DT04278E

248. Jessica C. Moreton, Jin Xiang Low, Katrina C. Penticoff, Seth M. Cohen, and Lauren Benz*, "An X-ray Photoelectron Spectroscopy Study of Postsynthetic Exchange in UiO-66" Langmuir 2022, 38, 1589-1599.
DOI: 10.1021/ACS.LANGMUIR1C03015

247. Sergio Ayala Jr. and Seth M. Cohen*, "PolyMOFs: Molecular Level Integration of MOFs and Polymers" Chapter 2 in Hybrid Metal-Organic Framework and Covalent Organic Framework Polymers, Smart Materials No. 39, published by the Royal Society of Chemistry, Ed. Bo Wang, 2022, 6-28.
DOI: 10.1039/9781839163456

246. Samar S. Sandhu, Yugender Goud Kotagiri, P. U. Ashvin Iresh Fernando, Mark Kalaj, Nicholas Tostado, Hazhir Teymourian, Erik M. Alberts, Travis Thornell, Glen Jenness, Steven P. Harvey, Seth M. Cohen*, Lee C. Moores*, and Joseph Wang*, "Green MIP-202(Zr) Catalyst: Degradation and Thermally Robust Biomimetic Sensing of Nerve Agents" J. Am. Chem. Soc. 2021, 143, 18261-18271.
DOI: 10.1021/JACS.1C08356

245. Johannes Karges*, Hyeonglim Seo, and Seth M. Cohen, "Synthesis of Tetranuclear Rhenium(I) Tricarbonyl Metallacycles" Dalton Trans. 2021, 50, 16147-16155.
DOI: 10.1039/D1DT02435C

244. Hyeonglim Seo, Kathleen Prosser, Mark Kalaj, Johannes Karges, Benjamin L. Dick, and Seth M. Cohen*, "Evaluating Metal-ligand Interactions of Metal-binding Isosteres Using Model Complexes" Inorg. Chem. 2021, 60, 17161-17172.
DOI: 10.1021/ACD.INORGCHEM.1C02433

243. Dominga Rogolino*, Lieve Naesens*, Jennifer Bartoli, Mauro Carcelli, Laura De Luca, Giorgio Pelosi, Ryjul W. Stokes, Ria Van Berwaer, Serena Vittorio, Annelies Stevaert, and Seth M. Cohen, "Exploration of the 2,3-Dihydroisoindole Pharmacophore for Inhibition of the Influenza Virus PA Endonuclease" Bioorg. Chem. 2021, 116, 105388.
DOI: 10.1016/J.BIOORG.2021.105388

242. Marcello B. Solomon, Carol Hua, Bun Chan, Tamara L. Church, Seth M. Cohen, Clifford P. Kubiak, Katrina A. Jolliffe, and Deanna M. D’Alessandro*, "The Electrochemical Reduction of a Flexible Mn(II) Salen-Based Metal-Organic Framework" Dalton Trans. 2021, 50, 12821-12825.
DOI: 10.1039/D1DT02589A

241. Seth M. Cohen* and Nathaniel L. Rosi*, "Postsynthetic Modification of Metal−Organic Frameworks" Inorg. Chem. 2021, 60, 11703-11705. (Guest Editor Introduction to Themed Issue)
DOI: 10.1021/ACS.INORGCHEM.1C02159958

240. Kelly Hunter, Jackson Wagner, Mark Kalaj, Seth M. Cohen, Wei Xiong*, and Francesco Paesani*, "Simulation Meets Experiment: Unraveling the Properties of Water in Metal-Organic Frameworks Through Vibrational Spectroscopy" J. Phys. Chem. C 2021, 125, 12451-12460.
DOI: 10.1021/ACS.JPCC.1C03145

239. Johannes Karges* and Seth M. Cohen*, "Metal Complexes as Antiviral Agents for SARS-CoV-2" ChemBioChem 2021, 22, 2600-2607.
DOI: 10.1002/cbic.202100186

238. Ashleigh Castner, Ben A. Johnson, Seth M. Cohen, Sascha Ott*, "Mimicking the Electron Transport Chain and Active Site of [FeFe] Hydrogenases in one Metal-Organic Framework: Factors that Influence Charge Transport" J. Am. Chem. Soc. 2021, 21, 7991–7999.
DOI: 10.1021/JACS.1C01361

237. Huan Zhang, Kundi Yang, Abbie Steinbrunner, Cecily Pryor, Maya Vulcan, Claire Kemp, Diego Orea, Chathura Paththamperuma, Zishuo Cheng, Allie Y. Chen, Seth M. Cohen, Richard C. Page, David L. Tierney, Michael W. Crowder*, "Spectroscopic and Biochemical Characterization of Metallo-b-lactamase IMP-1 with Dicarboxylic, Sulfonyl, and Thiol Inhibitors" Bioorg. Med. Chem. 2021, 40, 116183.
DOI: 10.1016/J.BMC.2021.116183

236. Kathleen E. Prosser, Alysia J. Kolhbrand, Heonglim Seo, Mark Kalaj, and Seth M. Cohen*, "19F-Tagged Metal Binding Pharmacophores for NMR Screening of Metalloenzymes" Chem. Commun. 2021, 57, 4934-4937.
DOI: 10.1039/D1CC01231B

235. Joseph M. Palomba, David M. Wirth, Jin Yeong Kim, Mark Kalaj, Evan M. Clarke, Gregory W. Peterson, Jonathan K. Pokorski, and Seth M. Cohen*, "Strong, Ductile MOF-Polyurethane Urea Composites" Chem. Mater. 2021, 33, 3164-3171.
DOI: 10.1021/ACS.CHEMMATER.0C04874

234. Ralph Freund, Stefano Canossa, Seth M. Cohen, Wei Yan, Hexiang Deng, Vincent Guillerm, Mohamed Eddaoudi, David G. Madden, David Fairen-Jimenez, Hao Lyu, Lauren K. Macreadie, Zhe Ji, Yuanyuan Zhang, Bo Wang, Frederik Haase, Christof Wöll, Orysia Zaremba, Jacopo Andreo, Stefan Wuttke, and Christian S. Diercks*, "25 years of Reticular Chemistry" Angew. Chem. Intl. Ed. 2021, 60, 23946-23974.
DOI: 10.1002/ANIE.202101644

233. Johannes Karges, Ryjul W. Stokes, and Seth M. Cohen*, "Metal Complexes for Therapeutic Applications" Trends Chem. 2021, 3, 523-534.
DOI: 10.1016/J.TRECHM.2021.03.006

232. Jin Yeong Kim, Kyle Barcus, and Seth M. Cohen*, "Controlled Two-Dimensional Alignment of Metal-organic Frameworks in Polymer Films" J. Am. Chem. Soc. 2021, 143, 3703-3706.
DOI: 10.1021/JACS.0C13459

231. Rebecca N. Adamek, Caitlin N. Suire, Ryjul W. Stokes, Monica K. Brizuela, Seth M. Cohen*, and Malcolm A. Leissring*, "Hydroxypyridinethione Inhibitors of Human Insulin-Degrading Enzyme" ChemMedChem 2021, 16, 1775-1787.
DOI: 10.1002/CMDC.202100111

230. Johannes Karges, Mark Kalaj, Milan Gembicky, and Seth M. Cohen*, "Re(I) Tricarbonyl Complexes as Coordinate Covalent Inhibitors for the SARS-CoV-2 Main Cysteine Protease" Angew. Chem. Intl. Ed. 2021, 60, 10716-10723.
DOI: 10.1002/ANIE.202016768

229. Jin Yeong Kim, Evan M. Clarke, and Seth M. Cohen*, "Current Trends in the Postsynthetic Modification of Framework Materials" Comprehensive Coordination Chemistry III 2021, 1, 1055-1073.
DOI: 10.1016/B978-0-08-102688-5.00087-8

228. Johannes Karges, Ryjul W. Stokes, and Seth M. Cohen*, "Photorelease of a Metal-Binding Pharmacophore from a Ru(II) Polypyridine Complex" Dalton Trans. 2021, 50, 2757-2765.
DOI: 10.1039/D0DT04290K

227. Yi-Sheng Lu, Sanahan Vijayakumar, Arnaud Chaix, Brian Pimentel, Kyle C. Bentz, Sheng Li, Adriano Chan, Charlotte Wahl, James Ha, Deborah Hunka, Gerry Boss, Seth M. Cohen, and Michael Sailor*, "Remote Detection of HCN, HF, and Nerve Agent Vapors Based on Self-Referencing, Dye-Impregnated Porous Silicon Photonic Crystals" ACS Sensors 2021, 6, 418-428.
DOI: 10.1021/ACSSENSORS.0C01931

226. Xinyi Gong, Karthikeyan Gnanasekaran, Zhijie Chen, Lee Robison, Megan C. Wasson, Kyle C. Bentz, Seth M. Cohen*, Omar K. Farha*, and Nathan C. Gianneschi*, "Insights into the Structure and Dynamics of Metal–Organic Frameworks via Transmission Electron Microscopy" J. Am. Chem. Soc. 2020, 142, 17224-17235.
DOI: 10.1021/JACS.0C08773

225. Kyle C. Bentz, Karthikeyan Gnanasekaran, Jake B. Bailey, Sergio Ayala Jr., F. Akif Tezcan, Nathan C. Gianneschi*, and Seth M. Cohen*, "Inside polyMOFs: Layered Structures in Polymer-Based Metal-Organic Frameworks" Chem. Sci. 2020, 11, 10523-10528.
DOI: 10.1039/D0SC03651J

224. Lucy Lin, Margaret Olson, Takashi Sugane, Lewis Turner, Margarita Tararina, Alexander L. Nielsen, Elbek Kurbanov, Sabine Pellett, Eric Johnson, Seth M. Cohen, Karen Allen, and Kim Janda*, "A Catch and Anchor Approach to Combat both Toxicity and Longevity of Botulinum Toxin A" J. Med. Chem. 2020, 63, 11100-11120.
DOI: 10.1021/ACS.JMEDCHEM.0C01006

223. Kyle S. Barcus and Seth M. Cohen*, "Free-Standing Metal-Organic Framework (MOF) Monolayers by Self-Assembly of Polymer-Grafted Nanoparticles" Chem. Sci. 2020, 11, 8433-8437.
DOI: 10.1039/D0SC03318A

222. Rebecca N. Adamek, Paul Ludford, Stephanie M Duggan, Yitzhak Tor*, and Seth M. Cohen*, "Identification of Adenosine Deaminase Inhibitors by Metal-binding Pharmacophore Screening" ChemMedChem 2020, 15, 2151-2156.
DOI: 10.1002/CMDC.202000271

221. Caitlyn A. Thomas, Zishuo Cheng, Kundi Yang, Elle Hellwarth, Cole J. Yurkiewicz, Faith M. Baxter, Sarah A. Fullington, Spencer A. Klinsky, Jen L. Otto, Allie Y. Chen, Seth M. Cohen, and Michael W. Crowder*, "Probing the mechanisms of inhibition for various inhibitors of metallo-β- lactamases VIM-2 and NDM-1" J. Inorg. Biochem. 2020, 210, 111123.
DOI: 10.1016/J.JINORGBIO.2020.111123

220. Mark Kalaj and Seth M. Cohen*, "Postsynthetic Modification: An Enabling Technology for the Advancement of Metal-Organic Frameworks" ACS Cent. Sci. 2020, 6, 1046-1057.
DOI: 10.1021/ACSCENTSCI.0C00690

219. Mark Kalaj, Kathleen E. Prosser, and Seth M. Cohen*, "Room Temperature Aqueous Synthesis of UiO-66 Derivatives via Postsynthetic Exchange" Dalton Trans. 2020, 49, 8841-8845.
DOI: 10.1039/D0DT01939A

218. Benjamin L. Dick, Ashay Patel, and Seth M. Cohen*, "Effect of Heterocycle Content on Metal Binding Isostere Coordination" Chem. Sci. 2020, 11, 6907-6914.
DOI: 10.1039/d0SC02717K

217. Paulo G. M. Mileo, Shichen Yuan, Sergio Ayala, Pu Duan, Rocio Semino, Seth M. Cohen*, Klaus Schmidt-Rohr*, and Guillaume Maurin*, " Structure of the Polymer Backbones in polyMOF Materials" J. Am. Chem. Soc. 2020, 142, 10863-10868.
DOI: 10.1021/JACS.0C04546

216. Kathleen E. Prosser, Ryjul W. Stokes, and Seth M. Cohen*, "Evaluation of 3-Dimensionality in Existing Approved and Experimental Drug Space" ACS Med. Chem. Lett. 2020, 11, 1292-1298.
DOI: 10.1021/ACSMEDCHEMLETT.0C00121

215. Mark Kalaj and Seth M. Cohen*, "Spray Coating of Catalytically Active MOF-Polythiourea through Postsynthetic Polymerization" Angew. Chem. Intl. Ed. 2020, 59, 13984-13989.
DOI: 10.1002/ANIE.202004205

214. Allie Y. Chen, Caitlyn Thomas, Pei W. Thomas, Kundi Yang, Zishou Cheng, Walter Fast*, Michael Crowder*, and Seth M. Cohen*, "Iminodiacetic Acid as a Novel Metal-Binding Pharmacophore for New Delhi Metallo-β-lactamase Inhibitor Development" ChemMedChem 2020, 15, 1272-1282.
DOI: 10.1002/CMDC.202000123

213. Jerika Chiong, Jie Zhu, Jake Bailey, Mark Kalaj, Rohit Subramanian, Wenqian Xu, Seth M. Cohen, F. Akif Tezcan*, "An Exceptionally Stable Metal-Organic Framework Constructed from Chelate-based Metal-Organic Polyhedra" J. Am. Chem. Soc. 2020, 142, 6907-6912.
DOI: 10.1021/JACS.0C01626

212. Jessica C. Moreton, Joseph M. Palomba, and Seth M. Cohen*, "Liquid-Phase Applications of Metal-Organic Framework Mixed-Matrix Membranes Prepared from Poly(ethylene-co-vinyl acetate)" ACS App. Poly. Mater. 2020, 2, 2063-2069.
DOI: 10.1021/ACSAPM.0C00230

211. Joseph M. Palomba, Mark Kalaj, and Seth M. Cohen*, "High-throughput Screening of MOFs for Breakdown of V-series Nerve Agents" ACS App. Mater. Inter. 2020, 12, 14672-14677.
DOI: 10.1021/ACSAMI.9B21693

210. Christine N. Morrison, Kathleen E. Prosser, Ryjul W. Stokes, Anna Cordes, Nils Metzler-Nolte, and Seth M. Cohen*, "Expanding Medicinal Chemistry into 3D Space: Metallofragments as 3D Scaffolds for Fragment-Based Drug Discovery" Chem. Sci. 2020, 11, 1216-1225 (selected as 'Pick of the Week' Jan. 15, 2020 by Chem. Sci.).
DOI: 10.1039/C9SC05586J

209. Mark Kalaj, Kyle C. Bentz, Sergio Ayala Jr., Joseph M. Palomba, Kyle S. Barcus, Yuji Katayama, and Seth M. Cohen*, "MOF-Polymer Hybrid Materials: From Simple Composites to Tailored Architectures" Chem. Rev. 2020, 120, 8267-8302.
DOI: 10.1021/ACS.CHEMREV.9B00575

208. Yuji Katayama, Mark Kalaj, Kyle S. Barcus, and Seth M. Cohen*, "Self-Assembly of Metal−Organic Framework (MOF) Nanoparticle Monolayers and Free-Standing Multilayers" J. Am. Chem. Soc. 2019, 141, 20000-20003.
DOI: 10.1021/JACS.9B10966

207. Cy V. Credille, Christine N. Morrison, Ryjul W. Stokes, Benjamin L. Dick, Yifan Feng, Jiaxing Sun, Yao Chen*, and Seth M. Cohen*, "SAR Exploration of Tight Binding Inhibitors of Influenza Virus PA Endonuclease" J. Med. Chem. 2019, 62, 9438-9449.
DOI: 10.1021/ACS.JMEDCHEM.9B00747

206. Kyle C. Bentz, Sergio Ayala Jr., Mark Kalaj, Seth M. Cohen*, "Polyacids as Modulators for the Synthesis of UiO-66" Aus. J. Chem. 2019, 72, 848-851.
DOI: 10.1071/CH19271

205. Allie Y. Chen, Pei W. Thomas, Zishou Cheng, Nasa Y. Xu, David L. Tierney, Michael, W. Crowder*, Walter Fast*, Seth M. Cohen*, "Investigation of Dipicolinic Acid Isosteres for the Inhibition of Metallo-b-Lactamases" ChemMedChem 2019, 14, 1271-1282.
DOI: 10.1002/CMDC.201900172

204. Mark Kalaj, Joseph M. Palomba, Kyle C. Bentz, Seth M. Cohen*, "Multiple Functional Groups in UiO-66 Improve Chemical Warfare Agent Simulant Degradation" Chem. Commun. 2019, 55, 5367-5370.
DOI: 10.1039/C9CC02252J

203. Pu Duan, Jessica C. Moreton, Sérgio R. Tavares, Rocio Semino, Guillaume Maurin*, Seth M. Cohen*, Klaus Schmidt-Rohr*, "Polymer Infiltration into Metal-organic Frameworks in Mixed-Matrix Membranes Detected In Situ by NMR" J. Am. Chem. Soc. 2019, 141, 7589-7595.
DOI: 10.1021/JACS.9B02789

202. Remo N. Widmer, Giulio I. Lampronti, Simone Anzellini, Romain Gaillac, Stefan Farsang, Chao Zhou, Ana M. Belenguer, Craig W. Wilson, Hannah Palmer, Annette K. Kleppe, Michael T. Wharmby, Xiao Yu, Seth M. Cohen, Shane G. Telfer, Simon A. T. Redfern, François-Xavier Coudert, Simon G. MacLeod, and Thomas D. Bennett*, "Pressure Promoted Low-temperature Melting of Metal–organic Frameworks" Nat. Mater. 2019, 18, 370-376.
DOI: 10.1021/ACSAMI.9B02539

201. Yuji Katayama, Kyle C. Bentz, and Seth M. Cohen*, "Defect-Free MOF-Based Mixed Matrix Membranes Obtained by Corona Crosslinking" ACS App. Mater. Inter. 2019, 11, 13029-13037.
DOI: 10.1021/ACSAMI.9B02539

200. Mark Kalaj, Mohammad R. Momeni, Kyle C. Bentz, Kyle S. Barcus, Joseph M. Palomba, Francesco Paesani, and Seth M. Cohen*, "Halogen bonding in UiO-66 Frameworks Promotes Superior Chemical Warfare Agent Simulant Degradation" Chem. Commun. 2019, 55, 3481-3484.
DOI: 10.1039/C9CC00642G

199. Louis Longley, Sean M. Collins, Shichun Li, Glen J. Smales, Ilknur Erucar, Ang Qiao, Jingwei Hou, Cara M. Doherty, Aaron W. Thornton, Anita J. Hill, Xiao Yu, Nicholas J. Terrill, Andrew J. Smith, Seth M. Cohen, Paul A. Midgley, David A. Keen, Shane G. Telfer, and Thomas D. Bennett*, “Flux Melting of Metal-Organic Frameworks” Chem. Sci. 2019, 10, 3592-3601.
DOI: 10.1039/C8SC04044C

198. Christian L. Perez, Amanda M. Barley-Levenson, Benjamin L. Dick, Peter F. Glatt, Yadira Martinez, Dionicio Siegel, Jeremiah D. Momper, Abraham A. Palmer*, and Seth M. Cohen*, "A Metal-Binding Pharmacophore Library Yields the Discovery of a Glyoxalase 1 Inhibition" J. Med. Chem. 2019, 62, 1609-1625.
DOI: 10.1021/ACS.JMEDCHEM.8B01868

197. Mark Kalaj, Michael S. Denny, Jr., Kyle C. Bentz, Joseph M. Palomba, and Seth M. Cohen*, "Nylon-MOF Composites via Postsynthetic Polymerization" Angew. Chem. Intl. Ed. 2019, 58, 2336-2340.
DOI: 10.1002/ANIE.201812655

196. Sergio Ayala Jr., Kyle C. Bentz, and Seth M. Cohen*, "Block co-polyMOFs: Morphology Control of Polymer-MOF Hybrid Materials" Chem. Sci. 2019, 10, 1746-1753.
DOI: 10.1039/C8SC04250K

195. Allie Y. Chen, Rebecca N. Adamek, Benjamin L. Dick, Cy V. Credille, Christine N. Morrison, and Seth M. Cohen*, "Targeting Metalloenzymes for Therapeutic Intervention" Chem. Rev. 2019, 119, 1323-1455.
DOI: 10.1021/ACS.CHEMREV.8B00201 

194. Cy V. Credille, Benjamin L. Dick, Ryjul W. Stokes, Rebecca N. Adamek, Nicholas Wu, Ian Wilson, and Seth M. Cohen*, "Structure-Activity Relationships in Metal-Binding Pharmacophores for Influenza Endonuclease" J. Med. Chem. 2018, 61, 10206-10217.
DOI: 10.1021/ACS.JMEDCHEM.8B01363

193. Michael S. Denny, Jr., Mark Kalaj, Kyle C. Bentz, and Seth M. Cohen*, "Multicomponent Metal–organic Framework Membranes for Advanced Functional Composites" Chem. Sci. 2018, 9, 8842-8849.
DOI: 10.1039/C8SC02356E

192. Joseph M. Palomba, Sergio Ayala Jr., and Seth M. Cohen*, "polyMOF Formation from Kinked Polymer Ligands via ortho- Substitution" Israel J. Chem. 2018, 58, 1123-1126 (invited article in honor of the Wolf Prize for Prof. Omar Yaghi).
DOI: 10.1002/IJCH.201800094

191. Kyle C. Bentz and Seth M. Cohen*, "Supramolecular Metallopolymers: From Linear Materials to Infinite Networks" Angew. Chem. Intl. Ed. 2018, 57, 14992-15001.
DOI: 10.1002/ANIE.201806912 and 10.1002/ANGE.201806912

190. Jing Li, Yaru Zhang,, Bruno Da Silva Sil Dos Santos, Yuyong Ma, Christian Perez, Yanling Yang, Junmin Peng, Seth M. Cohen, Stephen Hilton, and Raymond J. Deshaies*, "Epidithiodiketopiperazines Inhibit Protein Degradation by Targeting Proteasome Deubiquitinase Rpn11" Cell Chem. Biol. 2018, 25, P1350-1358.
DOI: 10.1016/J.CHEMBIOL.2018.07.012

189. Benjamin L. Dick and Seth M. Cohen*, "Metal-Binding Isosteres as New Scaffolds for Metalloenzyme Inhibitors" Inorg. Chem. 2018, 15, 9538-9543.
DOI: 10.1021/ACS.INORGCHEM.8B01632

188. Rebecca N. Adamek, Cy V. Credille, Benjamin L. Dick, and Seth M. Cohen*, "Isosteres of Hydroxypyridinethione as Druglike Pharmacophores for Metalloenzyme Inhibition" J. Biol. Inorg. Chem. 2018, 23, 1129-1138.
DOI: 10.1007/S00775-018-1593-1

187. Marcello Solomon, Aditya Rawal, James Hook, Seth M. Cohen, Clifford P. Kubiak, Katrina Jolliffe, Deanna D'Alessandro*, "Electroactive Co(III) Salen Metal Complexes and the Electrophoretic Deposition of their Porous Organic Polymers onto Glassy Carbon" RSC Adv. 2018, 8, 24128-24142.
DOI: 10.1039/C8RA04385J

186. Joseph M. Palomba, Cy V. Credille, Mark Kalaj, Jared B. DeCoste, Gregory W. Peterson, Trenton M. Tovar, and Seth M. Cohen*, "High-Throughput Screening of Solid-State Catalysts for Nerve Agent Degradation" Chem. Commun. 2018, 54, 5768 - 5771.
DOI: 10.1039/C8CC03255F

185. Ben A. Johnson, Asamanjoy Bhunia, Honghan Fei, Seth M. Cohen, and Sascha Ott*, "Development of a UiO-type Thin Film Electrocatalysis Platform with Redox Active Linkers" J. Am. Chem. Soc. 2018, 140, 2985-2994.
DOI: 10.1021/JACS.7B13077

184. Michael S. Denny, Jr., Lucas R. Parent, Joseph P. Patterson, Santosh Kumar Meena, Huy Pham, Patricia Abellan, Quentin M. Ramasse, Francesco Paesani,
Nathan C. Gianneschi,* and Seth M. Cohen*, "Transmission Electron Microscopy Reveals Deposition of Metal Oxide Coatings onto Metal−Organic Frameworks" J. Am. Chem. Soc. 2018, 140, 1348-1357.
DOI: 10.1021/JACS.7B10453

183. Le Wang, Douglas W. Agnew, Xiao Yu, Josh S. Figueroa*, and Seth M. Cohen*, “A Metal-Organic Framework with Exceptional Activity for C–H Bond Amination” Angew. Chem. Int. Ed. 2018, 57, 511-515.
DOI: 10.1002/ANIE.201709420.  Regrettably, this paper was retracted for lack of reproducibility, see DOI: 10.1002/anie.201709420.

182. Rocio Semino, Jessica C. Moreton, N. A. Ramsahye, Seth M. Cohen*, and Guillaume Maurin*, “Understanding the Origins of Metal-Organic Framework/Polymer Compatibility” Chem. Sci. 2018, 9, 315-324.
DOI: 10.1039/C7SC04152G 

181. Le Wang, Curtis E. Moore, and Seth M. Cohen*, “Coordinative Alignment to Achieve Ordered Guest Molecules in a Versatile Molecular Crystalline Sponge” Cryst. Growth Des. 2017, 17, 6174−6177.
DOI: 10.1021/ACS.CGD.7B01390

180. Lucas R. Parent, Huy Pham, Joseph P. Patterson, Michael S. Denny, Jr., Seth M. Cohen, Nathan C. Gianneschi*, and Francesco Paesani*, “Pore Breathing of Metal-Organic Frameworks by Environmental Transmission Electron Microscopy” J. Am. Chem. Soc. 2017, 139, 13973-13976.
DOI: 10.1021/JACS.7B06585

179. Giulia E. M. Schukraft, Sergio Ayala, Jr., Benjamin L. Dick, and Seth M. Cohen*, “Isoreticular Expansion of polyMOFs Achieves High Surface Area Materials” Chem. Commun. 2017, 53, 10684-10687.
DOI: 10.1039/C7CC04222A

178. Whitney R. Craig, Amy R. Marts, Tessa W. Baker, David P. Martin, Garrett C. Reed, Daniel T. DeGenova, Robert M. McCarrick, Michael W. Crowder*, Seth M. Cohen*, and David L. Tierney*, “Substituent Effects on the Coordination Chemistry of Metal-Binding Pharmacophores” Inorg. Chem. 2017, 56, 11721−11728.
DOI: 10.1021/ACS.INORGCHEM.7B01661

177. Allie Y. Chen, Pei W. Thomas, Alesha C. Stewart, Alexander Bergstrom, Zishuo Cheng, Callie Miller, Christopher R. Bethel, Steven H. Marshall, Cy V. Credille, Christopher L. Riley, Richard C. Page, Robert A. Bonomo*, Michael W. Crowder*, David L. Tierney*, Walter Fast*, and Seth M. Cohen*, “Dipicolinic Acid Derivatives as Inhibitors of New Delhi Metallo-β-lactamase-1” J. Med. Chem. 2017, 60, 7267-7283.
DOI: 10.1021/ACS.JMEDCHEM.7B00407

176. Seth M. Cohen*, “A Bioinorganic Approach to Fragment-based Drug Discovery Targeting Metalloenzymes” Acc. Chem. Res. 2017, 50, 2007-2016 (invited review).
DOI: 10.1021/ACS.ACCOUNTS.7B00242

175. Xiao Yu, Le Wang, and Seth M. Cohen*, “Photocatalytic Metal-Organic Frameworks for Organic Transformations” CrystEngComm 2017, 19, 4126-4136 (invited review).
DOI: 10.1039/C7CE00398F

174. Benjamin L. Dick, Ashay Patel, J. Andrew McCammon, and Seth M. Cohen*, “Effect of Donor Atom Identity on Metal Binding Pharmacophore Coordination” J. Biol. Inorg. Chem. 2017, 22, 605-613.
DOI: 10.1007/S00775-017-1454-3

173. Sergio Ayala, Jr., Zhenjie Zhang, and Seth M. Cohen*, “Hierarchical Structure and Porosity in UiO-66 polyMOFs” Chem. Commun. 2017, 53, 3058-3061.
DOI: 10.1039/C6CC10225E

172. Yao Chen*, Barry Lai, Zhenjie Zhang, and Seth M. Cohen*, “The Effect of Metalloprotein Inhibitors on Cellular Metal Ion Content and Distribution” Metallomics 2017, 9, 250-257.
DOI: 10.1039/C6MT00267F

171. Seth M. Cohen*, “The Postsynthetic Renaissance in Porous Solids” J. Am. Chem. Soc. 2017, 139, 2855-2863 (invited Perspectives article, selected for J. Am. Chem. Soc. Spotlight).
DOI: 10.1021/JACS.6B11259

170. Jing Li, Tanya Yakushi, Frank Parlati, Andrew L. Mackinnon, Christian Perez, Yuyong Ma, Kyle P. Carter, Sharon Colayco, Gavin Magnuson, Brock Brown, Kevin Nguyen, Stefan Vasile, Eigo Suyama, Layton H. Smith, Eduard Sergienko, Anthony B. Pinkerton, Thomas D.Y. Chung, Amy E. Palmer, Ian Pass, Sonja Hess, Seth M. Cohen, and Raymond J. Deshaies*, “Capzimin is a Potent and Specific Inhibitor of Proteasome Isopeptidase Rpn11” Nat. Chem. Biol. 2017, 13, 486-496.
DOI: 10.1038/NCHEMBIO.2326

169. Christian Perez, Jing Li, Frank Parlati, Matthieu Rouffet, Yuyong Ma, Han-Jie Zhou, Andrew L. Mackinnon, Tsui-Fen Chou, Raymond J. Deshaies*, and Seth M. Cohen*, “Discovery of an Inhibitor of the Proteasome Subunit Rpn11” J. Med. Chem. 2017, 60, 1343-1361.
DOI: 10.1021/ACS.JMEDCHEM.6B01379 (with correction at DOI: 10.1021/ACS.JMEDCHEM.7B00390)

168. Jinxing Li, Xiao Yu, Mingli Xu, Wenjuan Liu, Elodie Sandraz, Hsin Lan, Joseph Wang*, and Seth M. Cohen*, “Metal−Organic Frameworks as Micromotors with Tunable Engines” J. Am. Chem. Soc. 2017, 139, 611-614 (selected for J. Am. Chem. Soc. Spotlight, ACS Editors' Choice, highlighted in Nature Chemistry).
DOI: 10.1021/JACS.6B11899  


167. Jessica C. Moreton, Mike S. Denny, Jr., and Seth M. Cohen*, “High MOF Loading in Mixed-matrix Membranes Utilizing Styrene/butadiene Copolymers” Chem. Commun. 2016, 52, 14376-14379.
DOI: 10.1039/C6CC07329H

166. Mike S. Denny, Jr., Jessica C. Moreton, Lauren Benz*, and Seth M. Cohen*, “Metal-organic Frameworks for Membrane-based Separations” Nat. Rev. Mater. 2016, 1, Article number (16078).
DOI: 10.1038/NATREVMATS2016.78

165. Xiao Yu and Seth M. Cohen*, “Photocatalytic Metal−Organic Frameworks for Selective 2,2,2-Trifluoroethylation of Styrenes” J. Am. Chem. Soc. 2016, 138, 12320-12323.
DOI: 10.1021/JACS.6B06859

164. Teng-Hao Chen, Le Wang, Jonathan Trueblood, Vicki Grassian, and Seth M. Cohen*, “Poly(isophthalic acid)(ethylene oxide) as a Macromolecular Modulator for Metal−Organic Polyhedra” J. Am. Chem. Soc. 2016, 138, 9646-9654.
DOI: 10.1021/JACS.6B04971

163. Xiaoping Zhang, Zhenjie Zhang, Jake A. Boissonnault, and Seth M. Cohen*, “Design and Synthesis of Squaramide-Based MOFs as Efficient Hydrogen-Bonding Organocatalysts” Chem. Commun. 2016, 52, 8585-8588.
DOI: 10.1039/C6CC03190K

162. Cy V. Credille, Yao Chen, and Seth M. Cohen*, “Fragment-based Identification of Influenza Endonuclease Inhibitors” J. Med. Chem. 2016, 59, 6444-6454.
DOI: 10.1021/ACS.JMEDCHEM.6B00628

161. Seth M. Cohen*, Zhenjie Zhang, and Jake A. Boissonnault, “Toward ‘metalloMOFzymes’ – Metal-organic Frameworks with Single-site Metal Catalysts for Small Molecule Transformations” Inorg. Chem. 2016, 55, 7281-7290.
DOI: 10.1021/ACS.INORGCHEM.6B00828

160. Jared B. DeCoste*, Michael. S. Denny, Jr., Gregory W. Peterson, John J. Mahle, and Seth M. Cohen*, “Enhanced Aging Properties of HKUST-1 in Hydrophobic Mixed-Matrix Membranes for Ammonia Adsorption” Chem. Sci. 2016, 7, 2711-2716 (highlighted in C&EN Feb. 8, 2016).
DOI: 10.1039/C5DT04316F

159. Teng-Hao Chen, Andreas Schneemann, Roland A. Fischer, and Seth M. Cohen*, “Metal−organic Frameworks Constructed from Crown Ether-based 1,4-Benzenedicarboxylic Acid Derivatives” Dalton Trans. 2016, 45, 3063-3069.
DOI: 10.1039/C5DT04316F

158. Zhenjie Zhang, Ha Thi Hoang Nguyen, Stephen A. Miller, Ann Ploskonka, Jared DeCoste, and Seth M. Cohen*, “polyMOFs as Water Tolerant Materials for Selective Carbon Dioxide Separations” J. Am. Chem. Soc. 2016, 138, 920-925.
DOI: 10.1021/JACS.5B11034

157. Kevin B. Daniel, Cassandra E. Callmann, Nathan C. Gianneschi*, and Seth M. Cohen*, “Enzyme-Responsive Nanoparticles Release Cargo Upon Exposure to Matrix Metalloproteinase and Reactive Oxygen Species” Chem. Commun. 2016, 52, 2126-2128.
DOI: 10.1039/C5CC09164K  


156. Yeob Lee, Sangjun Kim, Honghan Fei, Jeung Ku Kang*, and Seth M. Cohen*, “Photocatalytic CO2 Reduction Using Visible Light by Metal-monocatecholato Species in a Metal-organic Framework” Chem. Commun. 2015, 51, 16549-16552.
DOI: 10.1039/C5CC04506A

155. Yao Chen and Seth M. Cohen*, "Investigating the Selectivity of Metalloenzyme Inhibitors in the Presence of Competing Metalloproteins" ChemMedChem 2015, 10, 1733-1738.
DOI: 10.1002/CMDC.201500293

154. Honghan Fei, Matthew D. Sampson, Yeob Lee, Clifford P. Kubiak*, and Seth M. Cohen*, "Photocatalytic CO2 Reduction to Formate Using a Mn(I) Molecular Catalyst in a Robust Metal-Organic Framework" Inorg. Chem. 2015, 54, 6821-6828.
DOI: 10.1021/ACS.INORGCHEM.5B00752

153. Mike S. Denny, Jr. and Seth M. Cohen*, "In Situ Modification of Metal-Organic Frameworks in Mixed- Matrix Membranes" Angew. Chem. Int. Ed. 2015, 54, 9029-9032 (selected as a ‘Very Important Paper’ by Angew. Chem. Int. Ed.).
DOI: 10.1002/ANIE.201504077

152. Joseph P. Patterson, Patricia Abellan, Mike S. Denny, Jr., Chiwoo Park, Nigel D. Browning, Seth M. Cohen, James E. Evans, and Nathan C. Gianneschi*, "Observing the Growth of Metal-Organic Frameworks by In-Situ Liquid Cell TEM" J. Am. Chem. Soc. 2015, 137, 7322-7328.
DOI: 10.1021/JACS.5B00817

151. Xiao Yu and Seth M. Cohen*, “Photocatalytic Metal-organic Frameworks for the Aerobic Oxidation of Arylboronic Acids" Chem. Commun. 2015, 51, 9880-9883.
DOI: 10.1039/C5CC01697E

150. Kevin Daniel, Eric Sullivan, Yao Chen, Joshua Chan, Patricia Jennings, Carol Fierke*, and Seth Cohen*, "A Dual-Mode HDAC Prodrug for Covalent Modification and Subsequent Inhibitor Release" J. Med. Chem. 2015, 58, 4812-4821.
DOI: 10.1021/ACS.JMEDCHEM.5B00539

149. Zhenjie Zhang, Ha Thi Hoang Nguyen, Stephen A. Miller, and Seth M. Cohen*, "polyMOFs: A New Class of Interconvertible Polymer-MOF Hybrid Materials" Angew. Chem. Int. Ed. 2015, 54, 6152-6157 (selected as a 'Hot Paper’ by Angew. Chem. Int. Ed., featured inside cover article; highlighted in Chemistry World April 30, 2015, C&EN May 11, 2015, and Nature Nanotechnology June, 2015).
DOI: 10.1002/ANIE.201502733

148. Christian Perez, Jean-Philippe Monserrat, Yao Chen, and Seth M. Cohen*, "Exploring Hydrogen Peroxide Responsive Thiazolidinone-Based Prodrugs" Chem. Commun. 2015, 51, 7116-7119.
DOI: 10.1039/C4CC09921D

147. Yeob Lee, Sangjun Kim, Jeung Ku Kang*, and Seth M. Cohen*, “Photocatalytic CO2 Reduction by a Mixed Metal (Zr/Ti), Mixed Ligand Metal-organic Framework Under Visible Light Irradiation” Chem. Commun. 2015, 51, 5735-5738.
DOI: 10.1039/C5CC00686D

146. Phuong V. Dau and Seth M. Cohen*, “A Bifunctional, Site-Isolated Metal-organic Framework-based Tandem Catalyst” Inorg. Chem. 2015, 54, 3134-3138.
DOI: 10.1021/IC502316V

145. Honghan Fei and Seth M. Cohen*, “Metalation of a Thiocatechol-Functionalized Zr(IV)-Based Metal–Organic Framework for Selective C–H Functionalization” J. Am. Chem. Soc. 2015, 137, 2191-2194.
DOI: 10.1021/JA5126885

144. JaeWook Shin, Min Kim, Jordi Cirera, Shawn Chen, Gregory J. Halder, Thomas A. Yersak, Francesco Paesani, Seth M. Cohen, and Ying Shirley Meng*, “MIL-101(Fe) as a Lithium-ion Battery Electrode Material: Relaxation and Intercalation Mechanism During Lithium Insertion” J. Mater. Chem. A 2015, 3, 4738-4744.
DOI: 10.1039/C4TA06694D

143. John F. Cahill, Honghan Fei, Seth M. Cohen, and Kimberly A. Prather*, “Characterization of Core-shell MOF Particles by Depth Profiling Experiments Using On-line Single Particle Mass Spectrometry” Analyst 2015, 140, 1510-1515.
DOI: 10.1039/C4AN01913J

142. Honghan Fei, Sonja Pullen, Andreas Wagner, Sascha Ott, and Seth M. Cohen*, “Functionalization of Robust Zr(IV)-based Metal–organic Framework Films via a Postsynthetic Ligand Exchange” Chem. Commun. 2015, 51, 66-69.
DOI: 10.1039/C4CC08218D  


141. Jun Nishida, Amr Tamimi, Honghan Fei, Sonja Pullen, Sascha Ott, Seth M. Cohen, and Michael D. Fayer*, “Structural Dynamics Inside a Functionalized Metal-organic Framework Probed by Ultrafast 2D IR Spectroscopy” Prod. Natl. Acad. Sci. USA 2014, 111, 18442-18447.
DOI: 10.1073/PNAS.1422194112

140. David P. Martin, Patrick G. Blachly, J. Andrew McCammon, and Seth M. Cohen*, “Exploring the Influence of the Protein Environment on Metal-Binding Pharmacophores” J. Med. Chem. 2014, 57, 7216-7135.
DOI: 10.1021/JM500984B

139. Phuong V. Dau and Seth M. Cohen*, “Modulating H2 Sorption in Metal-organic Frameworks via Ordered Functional Groups” Chem. Commun. 2014, 50, 12154-12157.
DOI: 10.1039/C4CC05265J

138. Corinne A. Allen and Seth M. Cohen*, “Exploration of Chemically Crosslinked Metal-organic Frameworks” Inorg. Chem. 2014, 53, 7014-7019.
DOI: 10.1021/IC500951B

137. Megan K. Thorson, David T. Puerta, Seth M. Cohen, and Amy M. Barrios*, “Inhibition of the Lymphoid Tyrosine Phosphatase: The Effect of Zinc(II) Ions and Chelating Ligand Fragments on Enzymatic Activity” Bioorg. Med. Chem. Lett. 2014, 24, 4019-4022.
DOI: 10.1016/J.BMCL.2014.06.016

136. Seth M. Cohen*, “Translating Bioinorganic Chemistry” ChemMedChem 2014, 9, 1087-1089 (invited contribution, guest editor introduction).
DOI: 10.1002/CMDC.201402148

135. Marco Taddei, Ferdinando Costantino, Riccardo Vivani, Stefano Sabatini, Sang-Ho Lim, and Seth M. Cohen, “The Use of a Rigid Tritopic Phosphonic Ligand for the Synthesis of a Robust Honeycomb-like Layered Zirconium Phosphonate Framework” Chem. Commun. 2014, 50, 5737-5740.
DOI: 10.1039/C4CC01253D

134. Honghan Fei and Seth M. Cohen*, “Robust, Catalytic Metal-Organic Framework with Open 2,2’-Bipyridine Sites” Chem. Commun. 2014, 50, 4810-4812.
DOI: 10.1039/C4CC01607F

133. David P. Martin, Patrick G. Blachly, Amy R. Marts, Tessa M. Woodruff, César A.F. de Oliveira, J. Andrew McCammon, David L. Tierney, and Seth M. Cohen*, “‘Unconventional’ Coordination Chemistry by Metal Chelating Fragments in a Metalloprotein Active Site” J. Am. Chem. Soc. 2014, 136, 5400-5406.
DOI: 10.1021/JA500616M

132. Honghan Fei, JaeWook Shin, Ying Shirley Meng, Mario Adelhardt, Jorg Sutter, Karsten Meyer, and Seth M. Cohen*, “Reusable Oxidation Catalysis Using Metal-Monocatecholato Species in a Robust Metal-Organic Framework” J. Am. Chem. Soc. 2014, 136, 4965-4973.
DOI: 10.1021/JA411627Z 


131. Sonja Pullen, Honghan Fei, Andreas Orthaber, Seth M. Cohen*, and Sascha Ott*, “Enhanced Photochemical Hydrogen Production by a Molecular Diiron Catalyst Incorporated into a Metal-Organic Framework” J. Am. Chem. Soc. 2013, 135, 16997-17003.
DOI: 10.1021/JA407176P

130. Joshua A. Day and Seth M. Cohen*, “Investigating the Selectivity of Metalloenzyme Inhibitors” J. Med. Chem. 2013, 56, 7997-8007.
DOI: 10.1021/JM401053M

129. Phuong V. Dau and Seth M. Cohen*, “The Influence of Nitro Groups on the Topology and Gas Sorption Property of Extended Zn(II)-Paddlewheel MOFs” CrystEngComm 2013, 15, 9304-9307.
DOI: 10.1039/C3CE41124A

128. Christian Perez, Kevin B. Daniel, and Seth M. Cohen*, “Evaluating Prodrug Strategies for Esterase-Triggered Release of Alcohols” ChemMedChem 2013, 8, 1662-1667.
DOI: 10.1002/CMDC.201300255

127. Amanda L. Garner, Jessica L. Fullagar, Joshua A. Day, Seth M. Cohen, and Kim D. Janda*, “Development of a High-Throughput Screen and Its Use in the Discovery of Streptococcus pneumoniaiae Immunoglobin A1 Protease Inhibitors” J. Am. Chem. Soc. 2013, 135, 10014-10017.
DOI: 10.1021/JA404180X

126. David P. Martin, Zachary S. Hann, and Seth M. Cohen*, “Metalloprotein-inhibitor Binding: Human Carbonic Anhydrase II as a Model for Probing Metal-ligand Interactions in a Metalloprotein Active Site” Inorg. Chem. 2013, 52, 12207-12215.
DOI: 10.1021/IC400295F

125. Sang Ho Lim and Seth M. Cohen*, “Self-assembled Supramolecular Clusters Based on Phosphines and Coinage Metals: Tetrahedra, Helicates, and Mesocates” Inorg. Chem. 2013, 52, 7862-7872.
DOI: 10.1021/IC302840X

124. Phuong V. Dau and Seth M. Cohen*, “Cyclometalated Metal-Organic Frameworks as Stable and Reusable Heterogeneous Catalysts for Allylic N-alkylation of Amines” Chem. Commun. 2013, 49, 6128-6130.
DOI: 10.1039/C3CC42119H

123. Honghan Fei, John F. Cahill, Kimberly A. Prather, and Seth M. Cohen*, “Tandem Postsynthetic Metal Ion and Ligand Exchange in Zeolitic Imidazolate Frameworks” Inorg. Chem. 2013, 52, 4011-4016.
DOI: 10.1021/IC400048G

122. Corinne A. Allen, Jake A. Boissonnault, Jordi Cirera, Ryan Gulland, Francesco Paesani, and Seth M. Cohen*, “Chemically Crosslinked Metal-Organic Frameworks” Chem. Commun. 2013, 49, 3200-3203.
DOI: 10.1039/C3CC40635K

121. Jessica L. Fullagar, Amanda L. Garner, Anjali K. Struss, Joshua A. Day, David P. Martin, Jing Yu, Xiaoqing Cai, Kim D. Janda*, and Seth M. Cohen*, “Antagonism of a Zinc Metalloprotease Using a Unique Metal-Chelating Scaffold Tropolones as Inhibitors of P. aeruginosa Elastase” Chem. Commun. 2013, 49, 3197-3199.
DOI: 10.1039/C3CC41191E

120. Kevin B. Daniel, Arpita Agrawal, Marianne Manchester, and Seth M. Cohen*, “Readily Accessible Fluorescent Probes for Sensitive Biological Imaging of Hydrogen Peroxide” ChemBioChem 2013, 14, 593-598.
DOI: 10.1002/CBIC.201200724

119. Phuong V. Dau, Luis R. Polanco and Seth M. Cohen*, “Dioxole Functionalized Metal–organic Frameworks” Dalton Trans. 2013, 42, 4013-4018.
DOI: 10.1039/C3DT32588A

118. Marco Taddei, Ferdinando Costantino, Andrea Ienco, Angiolina Comotti, Phuong V. Dau, and Seth M. Cohen*, “Synthesis, Breathing, and Gas Sorption Study of the First Isoreticular Mixed-linker Phosphonate Based Metal–organic Frameworks” Chem. Commun. 2013, 49, 1315-1317
DOI: 10.1039/C2CC38092G

117. Phuong V. Dau, Min Kim, and Seth M. Cohen*, “Site-selective Cyclometalation of a Metal-organic Framework” Chem. Sci. 2013, 4, 601-605.
DOI: 10.1039/C2SC21289G 


116. Gregory E. Cmarik, Min Kim, Seth M. Cohen, and Krista S. Walton*, “Tuning the Adsorption Properties of UiO-66 via Ligand Functionalization” Langmuir 2012, 28, 15606-15613.
DOI: 10.1021/LA3035352

115. Min Kim, John F. Cahill, Honghan Fei, Kimberly A. Prather, and Seth M. Cohen*, “Postsynthetic Ligand and Ion Exchange in Robust Metal-organic Frameworks” J. Am. Chem Soc. 2012, 134, 18082-18088.
DOI: 10.1021/JA3079219

114. Phuong V. Dau, Kristine K. Tanabe, and Seth M. Cohen*, “Functional Group Effects on Metal-organic Framework Topology” Chem. Commun. 2012, 48, 9370-9372.
DOI: 110.1039/C2CC34938H

113. Amanda L. Garner, Anjali K. Struss, Jessica L. Fullagar, Arpita Agrawal, Amira Y. Moreno, Seth M. Cohen*, and Kim D. Janda*, “3-Hydroxy-1-alkyl-2-methylpyridine-4(1H)-thiones: Inhibition of the Pseudomonas aeruginosa Virulence Factor LasB” ACS Med. Chem. Lett. 2012, 3, 668-672.
DOI: 10.1021/ML300128F

112. Phuong V. Dau, Min Kim, Sergio J. Garibay, Frédéric H. L. Münch, Curtis E. Moore, and Seth M. Cohen*, “Single-Atom Ligand Changes Affect Breathing in an Extended Metal–Organic Framework” Inorg. Chem. 2012, 51, 5671-5676.
DOI: 10.1021/ic202683s

111. David P. Martin and Seth M. Cohen*, “Nucleophile Recognition as an Alternative Inhibition Mode for Benzoic Acid Based Carbonic Anhydrase Inhibitors” Chem. Commun. 2012, 48, 5259-5261.
DOI: 10.1039/c2cc32013d

110. Alisa Tanakit, Matthieu Rouffet, David P. Martin, and Seth M. Cohen*, “Investigating Chelating Sulfonamides and their use in Metalloproteinase Inhibitors” Dalton Trans. 2012, 41, 6507-6515 (invited contribution).
DOI: 10.1039/c2dt12373h

109. Min Kim, Jake A. Boissonnault, Corrine A. Allen, Phuong V. Dau, and Seth M. Cohen*, "Functional Tolerance in an Isoreticular Series of Highly Porous Metal-organic Frameworks" Dalton Trans. 2012, 41, 6277-6282.
DOI: 10.1002/anie.201106429

108. Sang Ho Lim, Yongxuan Su and Seth M. Cohen*, “Supramolecular Tetrahedra of Phosphines and Coinage Metals” Angew. Chem. Int. Ed. 2012, 51, 5106-5109.
DOI: 10.1002/anie.201200730

107. Arpita Agrawal, Jamie DeSoto, Jessica L. Fullagar, Kasthuraiah Maddali, Shahrzad Rostami, Douglas D. Richman, Yves Pommier, and Seth M. Cohen*, “Probing Chelation Motifs in HIV Integrase Inhibitors” Prod. Natl. Acad. Sci. USA 2012, 109, 2251-2256.
DOI: 10.1073/pnas.1112389109

106. Min Kim* and Seth M. Cohen*, "Discovery, Development, and Functionalization of Zr(IV)-Based Metal-Organic Frameworks" CrystlEngComm 2012, Advanced Article (invited contribution).
DOI: 10.1039/C2CE06491J

105. Corinne A. Allen and Seth M. Cohen*, "Near-UV Photo-induced Modification in Isoreticular Metal-Organic Frameworks" J. Mat. Chem. 2012, 22, 10188-10194 (invited contribution).
DOI: 10.1039/C2JM15183A

104. Seth M. Cohen*, "Postsynthetic Methods for the Functionalization of Metal-Organic Frameworks" Chem. Rev. 2012, 112, 970-1000 (invited contribution).
DOI: 10.1021/CR200179U

103. Min Kim, John F. Cahill, Yongxuan Su, Kimberly A. Prather, and Seth M. Cohen, "Postsynthetic Ligand Exchange as a Route to Functionalization of ‘Inert’ Metal-Organic Frameworks" Chem. Sci. 2012, 3, 126-130.
DOI: 10.1039/C1SC00394A 


102. Min Kim, Jake A. Boissonnault, Phuong V. Dau, and Seth M. Cohen, "Metal-Organic Framework Regioisomers Based on Bifunctional Ligands" Angew. Chem. Int. Ed. 2011, 50, 12193-12196.
DOI: 10.1002/anie.201106429

101. Chao Chen, Corinne A. Allen, and Seth M. Cohen, "Tandem Postsynthetic Modification of Metal-Organic Frameworks Using an Inverse-Electron Demand Diels-Alder Reaction" Inorg. Chem. 2011, 50, 10534-10536.
DOI: 10.1021/ic2017598

100. Jody L. Major Jourden, Kevin B. Daniel, and Seth M. Cohen, "Investigation of Self-immolative Linkers in the Design of Hydrogen Peroxide Activated Metalloprotein Inhibitors" Chem. Commun. 2011, 47, 7968-7970.
DOI: 10.1039/C1CC12526E

99. Min Kim, John F. Cahill, Kimberly A. Prather, and Seth M. Cohen, "Postsynthetic Modification at Orthogonal Reactive Sites on Mixed, Bifunctional Metal-Organic Frameworks" Chem. Commun. 2011, 47, 7629-7631.
DOI: 10.1039/C1CC12101D

98. Matthieu Rouffet and Seth M. Cohen, "Emerging Trends in Metalloprotein Inhibition" Dalton Trans. 2011, 40, 3445-3454.
DOI: 10.1039/c0dt01743d

97. Kevin B. Daniel, Jody L. Major Jourden, and Seth M. Cohen, "Activation of Sulfonate Ester Based Matrix Metalloproteinase Proinhibitors by Hydrogen Peroxide" J. Biol. Inorg. Chem. 2011, 16, 313-323.
DOI: 10.1007/s00775-010-0727-x

96. Kristine K. Tanabe and Seth M. Cohen, "Postsynthetic Modification of Metal-Organic Frameworks - A Progress Report" Chem. Soc. Rev. 2011, 40, 498-519.
DOI: 10.1039/c0cs00031k

95. Min Kim, Sergio J. Garibay, and Seth M. Cohen, "Microwave-Assisted Cyanation of an Aryl Bromide Directly on a Metal-Organic Framework" Inorg. Chem. 2011, 50, 729-731.
DOI: 10.1021/ic102436b

94. Jennifer A. Jacobsen, Jessica L. Fullagar, Melissa T. Miller, and Seth M. Cohen, "Identifying Chelators for Metalloprotein Inhibitors Using a Fragment-Based Approach" J. Med. Chem. 2011, 54, 591-602.
DOI: 10.1021/jm101266s 


93. David P. Martin, Matthieu Rouffet, and Seth M. Cohen, "Illuminating Metal Ion Sensors - Benzimidazolesulfonamide Metal Complexes" Inorg. Chem. 2010, 49, 10226-10228.
DOI: 10.1021/ic101700t

92. Kristine K. Tanabe, Corinne Allen, and Seth M. Cohen, "Photochemical Activation of a Metal-Organic Framework to Reveal Functionality" Angew. Chem. Intl. Ed. 2010, 49, 9730-9733.
DOI: 10.1002/anie.201004736 (selected as a 'Hot Article' by Angew. Chem. Int. Ed., highlighted in Chemistry and Engineering News Nov. 22, 2010, and highlighted in ChemCatChem 2011, Advance Article).

91. Sergio J. Garibay and Seth M. Cohen, "Isoreticular Synthesis and Modification of Frameworks with the UiO-66 Topology" Chem. Commun. 2010, 46, 7700-7702.
DOI: 10.1039/C0CC02990D (selected as a 'Hot Article' by Chem. Commun.).

90. Sergio J. Garibay, Zhenqiang Wang, and Seth M. Cohen, "Evaluation of Heterogenous Metal-Organic Framework Organocatalysts Prepared by Postsynthetic Modification" Inorg. Chem. 2010, 49, 8086-8091.
DOI: 10.1021/ic1011549

89. Jody L. Major Jourden and Seth M. Cohen, "Hydrogen Peroxide Activated Matrix Metalloproteinase Inhibitors - A Prodrug Approach" Angew. Chem. Intl. Ed. 2010, 49, 6795-6797.
DOI: 10.1002/anie.201003819 (selected as a 'Hot Paper’ by Angew. Chem. Int. Ed.).

88. Johannes Schulze Wischeler, Alessio Innocenti, Daniela Vullo, Arpita Agrawal, Seth M. Cohen, Andreas Heine, Claudiu T. Supuran and Gerhard Klebe, "Bidentate Zinc Chelators for α-Carbonic Anhydrases that Produce a Trigonal Bipyramidal Coordination Geometry" ChemMedChem 2010, 5, 1609-1615.
DOI: 10.1002/cmdc.201000200

87. Kristine K. Tanabe and Seth M. Cohen, "Modular, Active, and Robust Lewis Acid Catalysts Supported on a Metal-Organic Framework" Inorg. Chem. 2010, 49, 6766–6774.
DOI: 10.1021/ic101125m

86. Matthieu Rouffet, César Augusto F. de Oliveira, Yael Udi, Arpita Agrawal, Irit Sagi, J. Andrew McCammon, and Seth M. Cohen, "From Sensors to Silencers: Quinoline- and Benzimidazole-Sulfonamides as Inhibitors for Zinc Proteases" J. Am. Chem. Soc. 2010, 132, 8232-8233.
DOI: 10.1021/ja101088j

85. Seth M. Cohen, "Modifying MOFs: New Chemistry, New Materials" Chem. Sci. 2010, 1, 32-36 (invited contribution for inaugural issue).
DOI: 10.1039/c0sc00127a

84. Christophe Volkringer and Seth M. Cohen, "Generating Reactive MILs: Isocyanate- and Isothiocyanate-bearing MILs through Postsynthetic Modification" Angew. Chem. Intl. Ed. 2010, 49, 4644-4648.
DOI: 10.1002/anie.201001527

83. Joseph L. Nguyen, Kristine K. Tananbe, and Seth M. Cohen, "Postsynthetic Diazeniumdiolate Formation and NO Release from MOFs" CrystEngComm 2010, 12, 2335-2338 (invited contribution, highlighted in Highlights in Chemical Technology Apr. 13, 2010).
DOI: 10.1039/c000154f

82. Joseph L. Nguyen and Seth M. Cohen, "Moisture-Resistant and Superhydrophobic Metal-Organic Frameworks Obtained via Postsynthetic Modification" J. Am. Chem. Soc. 2010, 132, 4560-4561.
DOI: 10.1021/ja100900c

81. Arpita Agrawal, Sherida L. Johnson, Jennifer A. Jacobsen, Melissa T. Miller, Li-Hsing Chen, Maurizio Pellecchia, and Seth M. Cohen, "Chelator Fragment Libraries for Targeting Metalloproteinases" ChemMedChem 2010, 2, 195-199.
DOI: 10.1002/cmdc.200900516

80. Jody L. Major Jourden and Seth M. Cohen, "Enzymatic Activation of a Matrix Metalloproteinase Inhibitor" Chem. Commun. 2010, 46, 1241-1243.
DOI: 10.1039/b923302d

79. Zhenqiang Wang, Kristine K. Tanabe, and Seth M. Cohen, "Tuning Hydrogen Sorption Properties of Metal-Organic Frameworks by Postsynthetic Covalent Modification" Chem. Eur. J. 2010, 16, 212-217.
DOI: 10.1002/chem.200902158

78. Jennifer A. Jacobsen, Jay R. Stork, Douglas Magde, and Seth M. Cohen, "Hydrogen-Bond Rigidified BODIPY Dyes" Dalton Trans. 2010, 39, 957-962.
DOI: 10.1039/n921772j

77. Jennifer A. Jacobsen, Jody L. Major Jourden, Melissa T. Miller, and Seth M. Cohen, "To Bind Zinc or not to Bind Zinc: An Examination of Innovative Approaches to Improved Metalloproteinase Inhibition" Biochim. Biophys. Acta - Mol. Cell Res. 2010, 1803, 72-94.
DOI: 10.1016/j.bbamcr.2009.08.006  


6. Zhenqiang Wang and Seth M. Cohen, "Modulating Metal-Organic Frameworks to Breathe: A Postsynthetic Covalent Modification Approach" J. Am. Chem. Soc. 2009, 131, 16675-16677 (highlighted in Chemistry and Engineering News Nov. 23, 2009).
DOI: 10.1021/ja907742z

75. Kate E. Stoll, William E. Draper, Joseph I. Kliegman, Misha V. Golynskiy, Rhoda A. T. Brew-Appiah, Rebecca K. Phillips, Hattie K. Brown, Wendy A. Breyer, Nicholas S. Jakubovics, Howard F. Jenkinson, Richard G. Brennan, Seth M. Cohen, and Arthur Glasfeld, "Characterization and Structure of the Manganese-responsive Transcriptional Regulator ScaR" Biochemistry 2009, 48, 10308–10320.
DOI: 10.1021/bi900980g

74. Seth M. Cohen, "Molecular Crystal Balls" Nature 2009, 461, 602-603 (invited News & Views article commenting on Kawamichi et al. Nature 2009, 461, 633-635).
DOI: 10.1038/461602a

73. Kristine K. Tanabe, and Seth M. Cohen, "Engineering a Metal-Organic Framework Catalyst by using Postsynthetic Modification" Angew. Chem. Intl. Ed. 2009, 48, 7424-7427 (selected as a 'Hot Paper’ by Angew. Chem. Int. Ed.; highlighted in Chemistry World Sept. 7, 2009).
DOI: 10.1002/anie.200903433

72. Sergio J. Garibay, Zhenqiang Wang, Kristine K. Tanabe, and Seth M. Cohen, "Postsynthetic Modification: A Versatile Approach Toward Multifunctional Metal-Organic Frameworks" Inorg. Chem. 2009, 48, 7341-7349.
DOI: 10.1021/ic900796n

71. Diego Romero-Perez, Arpita Agrawal, Jennifer A. Jacobsen, Yi-Long Yan, Robert Thomas, Seth M. Cohen, and Francisco J. Villarreal, "Effects of Novel Semiselective MMP Inhibitors on Ex vivo Cardiac Structure/Function" J. Cardiovas. Pharma. 2009, 53, 452-461.
DOI: 10.1097/FJC.0b013e3181a6aa83

70. Yi-Long Yan, Melissa T. Miller, Yuchen Cao, and Seth M. Cohen, "Synthesis of Hydroxypyrone- and Hydroxythiopyrone-based Matrix Metalloproteinase Inhibitors: Developing a Structure-activity Relationship" Bioorg. Med. Chem. Lett. 2009, 19, 1970-1976.
DOI: 10.1016/j.bmcl.2009.02.044

69. Zhenqiang Wang and Seth M. Cohen, "Postsynthetic Modification of Metal-Organic Frameworks" Chem. Soc. Rev. 2009, 38, 1315-1329.
DOI: 10.1039/b802258p

68. Arpita Agrawal, César Augusto F. de Oliveira, Yuhui Cheng, Jennifer A. Jacobsen, J. Andrew McCammon, and Seth M. Cohen, "Thioamide Hydroxypyrothiones Supersede Amide Hydroxypyrothiones in Potency Against Anthrax Lethal Factor" J. Med. Chem. 2009, 52, 1063-1074.
DOI: 10.1021/jm8013212

67. Zhenqiang Wang, Kristine K. Tanabe, and Seth M. Cohen, "Accessing Postsynthetic Modification in a Series of Metal-Organic Frameworks and the Influence of Framework Topology on Reactivity" Inorg. Chem. 2009, 48, 296-306.
DOI: 10.1021/ic801837t

66. Sergio J. Garibay, Jay R. Stork, and Seth M. Cohen, "The Use of Metalloligands in Metal-Organic Frameworks" Prog. Inorg. Chem. 2009, 56, 335-378.
DOI: N/A 


65. Van S. Thoi, Jay R. Stork, Edwards T. Niles, Ezra C. Depperman, David L. Tierney, and Seth M. Cohen, "Diamidodipyrrins: Versatile Bipyrrolic Ligands with Multiple Metal Binding Modes" Inorg. Chem. 2008, 47, 10533-10541.
DOI: 10.1021/ic8011876

64. Emily Dugan, Zhenqiang Wang, Marilyn Okamura, Annette Medina, and Seth M. Cohen, "Covalent Modification of a Metal-Organic Framework with Isocyanates: Probing Substrate Scope and Reactivity" Chem. Commun. 2008, 3366-3368 (featured cover article).
DOI: 10.1039/b806150e10

63. Faith E. Jacobsen, Matthew W. Buczynski, Edward A. Dennis, and Seth M. Cohen, "A Macrophage Cell Model for Selective Metalloprotein Inhibitor Design" ChemBioChem 2008, 9, 2087-2095.
DOI: 10.1002/cbic.200800148

62. Kristine K. Tanabe, Zhenqiang Wang, and Seth M. Cohen, "Systematic Functionalization of a Metal-Organic Framework via a Postsynthetic Modification Approach" J. Am. Chem. Soc. 2008, 130, 8508-8517.
DOI: 10.1021/ja801848j

61. Zhenqiang Wang and Seth M. Cohen, "Tandem Modification of Metal-Organic Frameworks via a Postsynthetic Approach" Angew. Chem. Intl. Ed. 2008, 47, 4699-4702 (highlighted in Angew. Chem. Int. Ed. 2007, 47, 4635-4637; DOI : 10.1002/anie.200801631).
DOI: 10.1002/anie.200800686

60. Arpita Agrawal, Diego Romero-Perez, Jennifer A. Jacobsen, Francisco J. Villarreal, and Seth M. Cohen, "Zinc-Binding Groups Modulate Selective Inhibition of MMPs " ChemMedChem 2008, 3, 812-820.
DOI: 10.1002/cmdc.200700290 


59. Zhenqiang Wang and Seth M. Cohen, "Postsynthetic Covalent Modification of a Neutral Metal-Organic Framework" J. Am. Chem. Soc. 2007, 129, 12368-12369.
DOI: 10.1021/ja074366o

58. Jay R. Stork, Van S. Thoi, and Seth M. Cohen, "Rare Examples of Transition Metal–Main Group Metal Heterometallic Metal-organic Frameworks from Gallium and Indium Dipyrrinato Complexes and Silver Salts: Synthesis and Framework Variability" Inorg. Chem. 2007, 46, 11213-11223.
DOI: 10.1021/ic7016159

57. Sergio J. Garibay, Jay R. Stork, Zhenqiang Wang, Seth M. Cohen, and Shane G. Telfer, "Enantiopure vs. Racemic Metalloligands: Impact on Metal-Organic Framework Structure and Synthesis" Chem. Commun. 2007, 4881-4883.
DOI: 10.1039/b712118k

56. Yi-Long Yan and Seth M. Cohen, "An Efficient Synthesis of 5-Amido-3-Hydroxy-4-Pyrones as Inhibitors of Matrix Metalloproteinases" Org. Lett. 2007, 9, 2517-2520.
DOI: 10.1021/ol0707665

55. Misha V. Golynskiy, Sheng Li, Virgil Woods Jr., and Seth M. Cohen, "Conformational Studies of the Manganese Transport Regulator (MntR) from Bacillus subtilis using Deuterium Exchange Mass Spectrometry" J. Biol. Inorg. Chem. 2007, 12, 699-709.
DOI: 10.1007/s00775-007-0216-z

54. Sara R. Halper, Jay R. Stork, and Seth M. Cohen, "Preparation and Characterization of Asymmetric α-Alkoxy Dipyrrin Ligands and their Metal Complexes" Dalton Trans. 2007, 1067-1074.
DOI: 10.1039/b615801c

53. Seth M. Cohen, "New Approaches for Medicinal Applications of Bioinorganic Chemistry" Curr. Opin. Chem. Biol. 2007, 11, 115-120 (invited contribution).
DOI: 10.1016/j.cbpa.2007.01.012

52. Faith E. Jacobsen, Jana A. Lewis, Katie J. Heroux, and Seth M. Cohen, "Characterization and Evaluation of Pyrone and Tropolone Chelators for use in Metalloprotein Inhibitors" Inorg. Chim. Acta 2007, 360, 264-272 (invited contribution).
DOI: 10.1016/j.ica.2006.07.044

51. Faith E. Jacobsen, Jana A. Lewis, and Seth M. Cohen, "The Design of Inhibitors for Medicinally Relevant Metalloproteins" ChemMedChem 2007, 2, 152-171 (invited contribution).
DOI: 10.1002/cmdc.200600204  


50. Misha V. Golynskiy, William A. Gunderson, Michael P. Hendrich, and Seth M. Cohen, " Metal Binding Studies and EPR Spectroscopy of the Manganese Transport Regulator MntR " Biochemistry 2006, 45, 15359-15372.
DOI: 10.1021/bi0607406

49. Van S. Thoi, Jay R. Stork, Douglas Magde, and Seth M. Cohen, "Luminescent Dipyrrinato Complexes of Trivalent Group 13 Metal Ions" Inorg. Chem. 2006, 45, 10688-10697.
DOI: 10.1021/ic061581h

48. Sara R. Halper, Loi Do, Jay R. Stork, and Seth M. Cohen, "Topological Control in Heterometallic Metal-Organic Frameworks by Anion Templating and Metalloligand Design" J. Am. Chem. Soc. 2006, 128, 15255-15268.
DOI: 10.1021/ja0645483

47. Faith E. Jacobsen, Robert M. Breece, William K. Myers, David L. Tierney, and Seth M. Cohen, "Model Complexes of Cobalt-Substituted Matrix Metalloproteinases: Tools for Inhibitor Design" Inorg. Chem. 2006, 45, 7306-7315.
DOI: 10.1021/ic060901u

46. Jana A. Lewis, John Mongan, J. Andrew McCammon, and Seth M. Cohen, "Evaluation and Binding Mode Prediction of Thiopyrone-Based Inhibitors of Anthrax Lethal Factor" ChemMedChem 2006, 1, 694-697.
DOI: 10.1002/cmdc/200600102

45. Faith E. Jacobsen, Jana A. Lewis, and Seth M. Cohen, "A New Role for Old Ligands: Discerning Chelators for Zinc Metalloproteinases" J. Am. Chem. Soc. 2006, 128, 3156-3157.
DOI: 10.1021/ja057957s

44. David T. Puerta, Mauro Botta, Christoph J. Jocher, Eric J. Werner, Stefano Avedano, Kenneth N. Raymond, and Seth M. Cohen, "Tris(pyrone) Chelates of Gd(III) as High Solubility MRI-CA" J. Am. Chem. Soc. 2006, 128, 2222-2223.
DOI: 10.1021/ja057954f

43. David T. Puerta, Michael O. Griffin, Jana A. Lewis, Diego Romero-Perez, Ricardo Garcia, Francisco J. Villarreal, and Seth M. Cohen, "Heterocyclic Zinc-Binding Groups for Use in Next Generation Matrix Metalloproteinase Inhibitors: Potency, Toxicity, and Reactivity" J. Biol. Inorg. Chem. 2006, 11, 131-138.
DOI: 10.1007/s00775-005-0053-x

42. Daniel Brayton, Faith E. Jacobsen, Seth M. Cohen, and Patrick J. Farmer, "A Novel Heterocyclic Atom Exchange Reaction with Lawesson's Reagent: One-pot Synthesis of Dithiomaltol" Chem. Commun. 2006, 206-208.
DOI: 10.1039/b511966a

41. Ba L. Tran and Seth M. Cohen, "Flavothionato Metal Complexes: Implications for the Use of Hydroxyflavothiones as Green Pesticides" Chem. Commun. 2006, 203-205.
DOI: 10.1039/b512185j  

40. David T. Puerta, John Mongan, Ba L. Tran, J. Andrew McCammon, and Seth M. Cohen, "Potent, Selective Pyrone-Based Inhibitors of Stromelysin-1" J. Am. Chem. Soc. 2005, 127, 14148-14149.
DOI: 10.1021/ja054558o

39. Drew L. Murphy, Mitchell R. Malachowski, Charles F. Campana, and Seth M. Cohen, "A Chiral, Heterometallic Metal-Organic Framework Derived from a Tris(Chelate) Coordination Complex" Chem. Commun. 2005, 5506-5508.
DOI: 10.1039/b510915a

38. Hongshan He, David T. Puerta, Seth M. Cohen, and Kenton R. Rodgers, "A Structural and Spectroscopic Study of Reactions between Chelating Zinc-Binding Groups and Mimics of the MMP and ADAM Catalytic Sites: The Coordination Chemistry of Metalloprotease Inhibition" Inorg. Chem. 2005, 44, 7431-7442.
DOI: 10.1021/ic050723p

37. Jana A. Lewis, Ba L. Tran, David T. Puerta, Evan M. Rumberger, David N. Hendrickson, and Seth M. Cohen, "Synthesis, Structure, and Spectroscopy of New Thiopyrone and Hydroxypyridinethione Transition Metal Complexes" Dalton Trans. 2005, 2588-2596 (featured cover article).
DOI: 10.1039/b505034k

36. Sara R. Halper and Seth M. Cohen, "Self-Assembly of Heteroleptic [Cu(dipyrrinato)(hfacac)] Complexes Directed by Fluorine-Fluorine Interactions" Inorg. Chem. 2005, 44, 4139-4141.
DOI: 10.1021/ic0504442

35. Misha V. Golynskiy, Talib C. Davis, John D. Helmann, Seth M. Cohen, "Metal-Induced Structural Organization and Stabilization of the Metalloregulatory Protein MntR" Biochemistry 2005, 44, 3380-3389.
DOI: 10.1021/bi0480741

34. Sara R. Halper and Seth M. Cohen, "Heterometallic Metal-Organic Frameworks Based on Tris(dipyrrinato) Coordination Complexes" Inorg. Chem. 2005, 44, 486-488.
DOI: 10.1021/ic048289z 

33. Jana A. Lewis and Seth M. Cohen, "Addressing Lead Toxicity: Complexation of Lead(II) with Thiopyrone and Hydroxypyridinethione O,S Mixed Chelators" Inorg. Chem. 2004, 43, 6534-6536.
DOI: 10.1021/ic0493696

32. Loi Do, Sara R. Halper, and Seth M. Cohen, "Helical Coordination Polymers and Cyclic Dimers Formed From Heteroleptic Thioether-Dipyrrinato Copper(II) Complexes" Chem. Commun. 2004, 2662-2663.
DOI: 10.1039/b411991f

31. David T. Puerta, Jana A. Lewis, and Seth M. Cohen, "New Beginnings for Matrix Metalloproteinase Inhibitors: Identification of High Affinity Zinc-Binding Groups" J. Am. Chem. Soc. 2004, 126, 8388-8389.
DOI: 10.1021/ja0485513

30. David T. Puerta and Seth M. Cohen, "A Bioinorganic Perspective on Matrix Metalloproteinase Inhibition" Curr. Top. Med. Chem. 2004, 4, 1551-1573.

29. Sara R. Halper and Seth M. Cohen, "Self-Assembly of Two Distinct Supramolecular Motifs in a Single Crystalline Framework" Angew. Chem. Intl. Ed. 2004, 43, 2385-2388.
DOI: 10.1002/anie.200353520

28. Faith E. Jacobsen and Seth M. Cohen, "Using Model Complexes to Augment and Advance Metalloproteinase Inhibitor Design" Inorg. Chem. 2004, 43, 3038-3047 (featured cover article).
DOI: 10.1021/ic035388o

27. Sara R. Halper, Mitchell R. Malachowski, Heather M. Delaney, and Seth M. Cohen, "Heteroleptic Copper Dipyrromethene Complexes: Synthesis, Structure, and Coordiation Polymers" Inorg. Chem. 2004, 43, 1242-1249.
DOI: 10.1021/ic0352295 

26. Jana A. Lewis, David T. Puerta, and Seth M. Cohen, "Metal Complexes of the trans-influencing Ligand Thiomaltol" Inorg. Chem. 2003, 42, 7455-7459.
DOI: 10.1021/ic0347135

25. Scot A. Lieser, Talib C. Davis, John D. Helmann, Seth M. Cohen, "DNA-Binding and Oligomerization Studies of the Manganese(II) Metalloregulatory Protein MntR from B. subtilis" Biochemistry 2003, 42, 12634-12642.
DOI: 10.1021/bi0350248

24. Sara R. Halper and Seth M. Cohen, "Synthesis, Structure, and Spectroscopy of Phenylacetylene Rods Incorporating Meso-Substituted Dipyrrin Ligands" Chem. Eur. J. 2003, 9, 4661-4669.
DOI : 10.1002/chem.200305041

23. David T. Puerta, Julie R. Schames, Richard H. Henchman, J. Andrew McCammon, and Seth M. Cohen, "From Model Complexes to Metalloprotein Inhibition: A Synergistic Approach to Structure-Based Drug Discovery" Angew. Chem. Intl. Ed. 2003, 42, 3772-3774.
DOI: 10.1002/anie.200351433

22. David T. Puerta and Seth M. Cohen, "Synthesis and structure of the hexameric, dodecanuclear metallamacrocycle [(5,3-methylphenylpyrazole)2Zn2(OCH2CH2S)]6" Chem. Commun. 2003, 1278-1279.
DOI: 10.1039/b300453h

21. David T. Puerta and Seth M. Cohen, "Examination of Novel Zinc-Binding Groups for Use in Matrix Metalloproteinase Inhibitors" Inorg. Chem. 2003, 42, 3423-3430.
DOI: 10.1021/ic026029g 

20. David T. Puerta and Seth M. Cohen, "Elucidating Drug-Metalloprotein Interactions with Tris(pyrazolyl)borate Model Complexes" Inorg. Chem. 2002, 41, 5075-5082.
DOI: 10.1021/ic0204272

19. Seth M. Cohen and Sara R. Halper, "Dipyrromethene Complexes of Iron" Inorg. Chim. Acta 2002, 341, 12-16 (invited contribution).
DOI: 10.1016/S0020-1693(02)01176-3

18. David T. Puerta and Seth M. Cohen, "[(TpMe,Ph)2Zn2(H3O2)]ClO4: A New H3O2 Species Relevant to Zinc Proteinases" Inorg. Chim. Acta 2002, 337, 459-462 (invited contribution).
DOI: 10.1016/S0020-1693(02)00994-5   

17. Stéphane Petoud, Gilles Muller, Evan G. Moore, Jide Xu, Jurek Sokolnicki, James P. Riehl, Uyen N. Le, Seth M. Cohen, and Kenneth N. Raymond, "Brilliant Sm, Eu, Tb, and Dy Chiral Lanthanide Complexes with Strong Circularly Polarized Luminescence" J. Am. Chem. Soc. 2007, 129, 77-83 .
DOI: 10.1021/ja064902x

16. Stéphane Petoud, Seth M. Cohen, Jean-Claude Bünzli, and Kenneth N. Raymond, "Stable, High Quantum Yield Lanthanide Luminescence Agents: Multidentate 2-Hydroisophthalamide Complexes of Sm3+, Eu3+, Tb3+, Dy3+ in Aqueous Solution" J. Am. Chem. Soc. 2003, 125, 13324-13325.
DOI: 10.1021/ja0379363

15. Carmen M. Barnés, Stéphane Petoud, Seth M. Cohen, and Kenneth N. Raymond, "Iron Uptake in Horse Spleen Ferritin Probed by the Kinetically Inert Inhibitor, [Cr(TREN)(H2O)(OH)]2+, and a New Luminescent Tb(III) Reagent" J. Biol. Inorg. Chem. 2003, 8, 195-205.
DOI: 10.1007/s00775-002-0409-4

14. Adam P. Silverman, Weiming Bu, Seth M. Cohen,and Stephen J. Lippard, "Effects of Spectator Ligands on the Specific Recognition of Intrastrand Platinum-DNA Cross-links by High Mobility Group Box and TATA-Binding Proteins" J. Biol. Chem. 2002, 276, 38774-38780.
DOI: 10.1074/jbc.M206979200

13. Min Wei, Seth M. Cohen, Adam P. Silverman, and Stephen J. Lippard, "Effects of Spectator Ligands on the Specific Recognition of Intrastrand Platinum-DNA Cross-links by High Mobility Group Box and TATA-Binding Proteins" J. Biol. Chem. 2001, 276, 38774-38780.

12. Seth M. Cohen and Stephen J. Lippard, "Cisplatin: From DNA Damage to Cancer Chemotherapy" Prog. Nucleic Acid Res. Mol. Biol. 2001, 67, 93-130.

11. Sharad P. Hajela, Adam R. Johnson, Jide Xu, Christopher J. Sunderland, Seth M. Cohen, Dana L. Caulder, and Kenneth N. Raymond, "Synthesis of Homochiral Tris(2-alkyl-2-aminoethyl)amine Derivatives from Chiral a-Amino Aldehydes and Their Application in the Synthesis of Water Soluble Chelators" Inorg. Chem. 2001, 40, 3208-3216.
DOI: 10.1021/ic001021x

10. Seth M. Cohen, Stéphane Petoud, and Kenneth N. Raymond, "Synthesis and Metal Binding Properties of Salicylate, Catecholate, and Hydroxypyridinonate Functionalized Dendrimers" Chem. Eur. J. 2000, 7, 272-279.

9. Seth M. Cohen, Jide Xu, Emil Radkov, Kenneth N. Raymond, Mauro Botta, Alessandro Barge, and Silvo Aime, "Synthesis and Relaxation Properties of Mixed Gadolinium Hydroxypyridinonate MRI Contrast Agents" Inorg. Chem. 2000, 39, 5747-5756.
DOI: 10.1021/ic000563b

8. Judith N. Burstyn, Wendy J. Heiger-Bernays, Seth M. Cohen, and Stephen J. Lippard, "Formation of cis-Diamminedichloroplatinum(II) Cross-links on DNA is Flanking Sequence Independent" Nucleic Acids Res. 2000, 28, 4237-4243.

7. Seth M. Cohen, Yuji Mikata, Qing He, and Stephen J. Lippard, "HMG-Domain Protein Recognition of Cisplatin 1,2-Intrastrand d(GpG) Cross-links in Purine-Rich Sequence Contexts" Biochemistry 2000, 39, 11771-11776.
DOI: 10.1021/bi001352l

6. Seth M. Cohen, Brendon O'Sullivan, and Kenneth N. Raymond, "Mixed Hydroxypyridinonate Ligands as Iron Chelators" Inorg. Chem. 2000, 39, 4339-4346.
DOI: 10.1021/ic000239g

5. Seth M. Cohen and Kenneth N. Raymond, "Catecholate/Salicylate Heteropodands: Demonstration of a Catecholate to Salicylate Coordination Change" Inorg. Chem. 2000, 39, 3624-3631.
DOI: 10.1021/ic990608c

4. Seth M. Cohen, Elizabeth R. Jamieson, and Stephen J. Lippard, "Enhanced Binding of the TATA-Binding Protein to TATA Boxes Containing Flanking Cisplatin 1,2-Cross-links" Biochemistry 2000, 39, 8259-8265.
DOI: 10.1021/bi0004495

3. Seth M. Cohen, Stéphane Petoud, and Kenneth N. Raymond, "A Novel Salicylate-based Macrobicycle with a 'Split Personality'" Inorg. Chem. 1999, 38, 4522-4529.
DOI: 10.1021/ic990411k

2. Seth M. Cohen, Michel Meyer, and Kenneth N. Raymond, "Enterobactin Protonation and Iron Release: Hexadentate Tris-Salicylate Ligands as Models for Triprotonated Ferric Enterobactin" J. Am. Chem. Soc. 1998, 120, 6277-6286.
DOI: 10.1021/ja973442s

1. Michel Meyer, Jason R. Telford, Seth M. Cohen, David White, Jide Xu, and Kenneth N. Raymond, "High Yield Synthesis of the Enterobactin Trilactone and Evaluation of Derivative Siderophore Analogs" J. Am. Chem. Soc. 1997, 119, 10093-10103.
DOI: 10.1021/ja970718n 

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